This vignette outlines the steps of inference, analysis and visualization of niche for a Visium HD spatial dataset using SpatialNiche. We showcase SpatialNiche’s diverse functionalities by applying it to a Visium HD data on cells from Lymphangioleiomyomatosis (LAM, diseased) human lung from a patient.

SpatialNiche requires raw Visium HD spaceranger output and optionally processed gene expression data of cells/bins from Seurat objects as the user input and models the niche based on a specific cell type or gene expression.

Upon infering the niche, SpatialNichet provides functionality for further data exploration, analysis, and visualization.

Load the required libraries

library(SpatialNiche)
library(ggplot2)
library(dplyr)
library(scattermore)

Part I: Data input & processing and initialization of SpatialNiche list containing barcodes and images tibble

SpatialNiche requires two user inputs: one is the path to outs directory of the spaceranger output of the Visium HD dataset, and the other is the bins size you want to load.

Starting from spaceranger output

ptm = Sys.time()

localdir <- "../../../4_em/outs" # path to outs directory of the spaceranger output of the Visium HD dataset

DataHD<-Load_Spatial_Data(localdir, size = '008um') #loading the data using the path and the bin size

bcsHD<-DataHD$barcodes #pulling the barcodes tibble out for easier access

head(bcsHD) #look at the top entries
#> # A tibble: 6 × 12
#>   barcode   tissue   row   col imagerow imagecol imagerow_scaled imagecol_scaled
#>   <chr>     <fct>  <int> <int>    <dbl>    <dbl>           <dbl>           <dbl>
#> 1 s_008um_… 0          0     0   27281.   -69.7             620.          -1.58 
#> 2 s_008um_… 0          0     1   27282.   -38.0             620.          -0.863
#> 3 s_008um_… 0          0     2   27282.    -6.19            620.          -0.141
#> 4 s_008um_… 0          0     3   27282.    25.6             620.           0.582
#> 5 s_008um_… 0          0     4   27282.    57.4             620.           1.30 
#> 6 s_008um_… 0          0     5   27282.    89.1             620.           2.03 
#> # ℹ 4 more variables: imagerow_scaled_round <dbl>, imagecol_scaled_round <dbl>,
#> #   height <int>, width <int>

Part II: Adding dconvolution information to SpatialNiche barcodes tibble

SpatialNiche supports import of spacexr’s RCTD based deconvolution information. Thre RCTD result can be directly loaded as an rds object and imported directly into the barcodes tibble.

Starting from RCTD output

ptm = Sys.time()

DeconvolutionHD<-Load_RCTD('../../../RCTD_d4_SCT.rds') #load rds object of RCTD results

bcsHD<-Add_Deconvolution_Info(bcsHD,DeconvolutionHD,addWeights=FALSE) #use in-built function to import RCTD deconvolution results

bcsHD<-bcsHD %>% na.omit() # remove blank barcodes with no deconvolution information

head(bcsHD[, c(1,13:15)]) #look at the top entries with deconvolution information
#> # A tibble: 6 × 4
#>   barcode             DeconvolutionClass DeconvolutionLabel1 DeconvolutionLabel2
#>   <chr>               <chr>              <chr>               <chr>              
#> 1 s_008um_00102_0021… singlet            IM                  pDC                
#> 2 s_008um_00102_0021… reject             IM                  LAMCORE-3          
#> 3 s_008um_00102_0021… reject             IM                  LAMCORE-1          
#> 4 s_008um_00102_0021… singlet            Mast-Basophil       Plasma             
#> 5 s_008um_00102_0022… reject             AF2                 AT2                
#> 6 s_008um_00102_0022… singlet            LAMCORE-1           Plasma

Part III: Creating niche information

SpatialNiche creates niche information based on a specific cell type or gene expression.The niche information is defined based on a sepcific distance away from the bins/cells of interest.

Defining niche based on a cell type

ptm = Sys.time()

PeripheryBCs<-Get_Periphery(barcodes=bcsHD, celltype='LAMCORE-1',distance=50,data.dir = localdir)

bcsHD$Periphery<-NA
bcsHD$Periphery[bcsHD$barcode%in%PeripheryBCs]<-"50 micron"
bcsHD$Periphery[is.na(bcsHD$Periphery)]<-"Tissue"
bcsHD$Periphery[bcsHD$Periphery=="Tissue" & bcsHD$DeconvolutionLabel1=='LAMCORE-1']<-'LAMCORE-1'

head(bcsHD[, c(1,14:16)]) #look at the top entries with cell based niche information
#> # A tibble: 6 × 4
#>   barcode               DeconvolutionLabel1 DeconvolutionLabel2 Periphery
#>   <chr>                 <chr>               <chr>               <chr>    
#> 1 s_008um_00102_00216-1 IM                  pDC                 Tissue   
#> 2 s_008um_00102_00217-1 IM                  LAMCORE-3           Tissue   
#> 3 s_008um_00102_00218-1 IM                  LAMCORE-1           Tissue   
#> 4 s_008um_00102_00219-1 Mast-Basophil       Plasma              Tissue   
#> 5 s_008um_00102_00220-1 AF2                 AT2                 Tissue   
#> 6 s_008um_00102_00221-1 LAMCORE-1           Plasma              LAMCORE-1

Defining niche based on gene expression

ptm = Sys.time()

em_d4 <- readRDS("../../../em_d4_SCT.rds")

bcsHD<-Add_Expression(bcsHD,em_d4,c("PMEL"))
#> Loading required package: Seurat
#> Loading required package: SeuratObject
#> Loading required package: sp
#> 'SeuratObject' was built with package 'Matrix' 1.7.0 but the current
#> version is 1.7.3; it is recomended that you reinstall 'SeuratObject' as
#> the ABI for 'Matrix' may have changed
#> 
#> Attaching package: 'SeuratObject'
#> The following objects are masked from 'package:base':
#> 
#>     intersect, t

PeripheryGCs<-Get_Gene_Periphery(barcodes=bcsHD, gene=c("PMEL"), seurat=em_d4,distance=50,data.dir = localdir)

bcsHD$Peripheryg<-NA
bcsHD$Peripheryg[bcsHD$barcode%in%PeripheryGCs]<-"50 micron"
bcsHD$Peripheryg[is.na(bcsHD$Peripheryg)]<-"Tissue"
bcsHD$Peripheryg[bcsHD$Peripheryg=="Tissue" & bcsHD$PMEL>0]<-'PMEL'

head(bcsHD[, c(1,14:18)]) #look at the top entries with gene expression based niche information
#> # A tibble: 6 × 6
#>   barcode     DeconvolutionLabel1 DeconvolutionLabel2 Periphery  PMEL Peripheryg
#>   <chr>       <chr>               <chr>               <chr>     <dbl> <chr>     
#> 1 s_008um_00… IM                  pDC                 Tissue        0 Tissue    
#> 2 s_008um_00… IM                  LAMCORE-3           Tissue        0 50 micron 
#> 3 s_008um_00… IM                  LAMCORE-1           Tissue        0 50 micron 
#> 4 s_008um_00… Mast-Basophil       Plasma              Tissue        0 50 micron 
#> 5 s_008um_00… AF2                 AT2                 Tissue        0 50 micron 
#> 6 s_008um_00… LAMCORE-1           Plasma              LAMCORE-1     0 50 micron

Part IV: Visualizing niche results

Upon infering the niche information, SpatialNiche provides various functionality for further data exploration, analysis, and visualization. Specifically:

slicing the dataset into smaller ROIs

SliceA<-Get_Square('s_008um_00128_00230-1',250,bcsHD)

head(SliceA)
#> [1] "s_008um_00112_00214-1" "s_008um_00112_00216-1" "s_008um_00112_00217-1"
#> [4] "s_008um_00112_00218-1" "s_008um_00112_00221-1" "s_008um_00112_00222-1"

SliceB<-Get_Rectangle('s_008um_00331_00466-1',300,0.65,1.1,bcsHD)

head(SliceB)
#> [1] "s_008um_00311_00456-1" "s_008um_00311_00457-1" "s_008um_00311_00459-1"
#> [4] "s_008um_00311_00460-1" "s_008um_00311_00461-1" "s_008um_00311_00462-1"

SliceC<-Get_Circle('s_008um_00128_00230-1',125,bcsHD, localdir)

head(SliceC)
#> [1] "s_008um_00113_00226-1" "s_008um_00113_00227-1" "s_008um_00113_00228-1"
#> [4] "s_008um_00113_00229-1" "s_008um_00113_00230-1" "s_008um_00113_00231-1"

Visualizing based on deconvolution information

bcsHD %>% filter(DeconvolutionClass=="singlet") %>%
  ggplot(aes(x = imagecol_scaled, y = -imagerow_scaled,color=DeconvolutionLabel1)) +
  Geom_Spatial(data = DataHD$images, aes(grob = grob), x = 0.5, y = 0.5)+
  geom_scattermore(pointsize = 2,pixels = rep(2000,2))+
  coord_cartesian(expand = FALSE) +
  xlab("") +
  ylab("") +
  theme_set(theme_bw(base_size = 10))+
  theme_minimal() +
  theme(axis.text = element_blank(),
        panel.grid.minor = element_blank(),
        panel.grid.major = element_blank())+
  #geom_rect(aes(xmin=DFRectA$Xmin, xmax=DFRectA$Xmax, ymin=DFRectA$Ymax, ymax=DFRectA$Ymin),fill=NA,color="black",linewidth=1)+
  #geom_circle(aes(x0=DFRectC$Xavg, y0=DFRectC$Yavg, r=DFRectC$rad),fill=NA,color="black",linewidth=1)+
  #scale_color_manual(values=ColorPalette())
  NoLegend()


bcsHD  %>%
  ggplot(aes(x = imagecol_scaled, y = -imagerow_scaled,color=DeconvolutionLabel1)) +
  Geom_Spatial(data = DataHD$images, aes(grob = grob), x = 0.5, y = 0.5) +
  geom_point(shape=16,size=2)+ #sahpe 15=square 16=circle
  coord_cartesian(expand = FALSE) +
  #scale_color_manual(values = ColorPalette(),na.value = NA) +
  xlab("") +
  ylab("") + theme_set(theme_bw(base_size = 10))+
  theme_minimal() +
  theme(axis.text = element_blank())#+NoLegend()

Visualizing based on niche information

bcA=bcsHD[bcsHD$Periphery!='Tissue',]

bcA %>%
  ggplot(aes(x = imagecol_scaled, y = -imagerow_scaled,color=Periphery)) +
  Geom_Spatial(data = DataHD$images, aes(grob = grob), x = 0.5, y = 0.5) +
  geom_scattermore(pointsize = 2,pixels = rep(2000,2)) +
  scale_color_manual(values=c('green','red','grey')) +
  coord_cartesian(expand = FALSE) +
  xlab("") +
  ylab("") +
  theme_set(theme_bw(base_size = 10)) +
  theme_minimal() +
  theme(axis.text = element_blank(),
        panel.grid.minor = element_blank(),
        panel.grid.major = element_blank())


bcA=bcsHD[bcsHD$Peripheryg!='Tissue',]

bcA %>%
  ggplot(aes(x = imagecol_scaled, y = -imagerow_scaled,color=Peripheryg)) +
  Geom_Spatial(data = DataHD$images, aes(grob = grob), x = 0.5, y = 0.5) +
  geom_scattermore(pointsize = 2,pixels = rep(2000,2)) +
  scale_color_manual(values=c('green','red','grey')) +
  coord_cartesian(expand = FALSE) +
  xlab("") +
  ylab("") +
  theme_set(theme_bw(base_size = 10)) +
  theme_minimal() +
  theme(axis.text = element_blank(),
        panel.grid.minor = element_blank(),
        panel.grid.major = element_blank())

Part V: Calculating distance information

SpatialNiche is also capable of creating distance information by translating the pixel sizes to the micron scale. The results are output as a distane matrix that can be converted to a dataframe for use.

Defining niche based on a cell type

ptm = Sys.time()

em_d4G1 <- readRDS("../../../KWB/em_d4_G1.rds")

spatial.locs = Seurat::GetTissueCoordinates(em_d4G1, scale = NULL, cols = c("imagerow", "imagecol"))
spatial.locs = spatial.locs[,1:2]

spot.size = 8

conversion.factor = spot.size/em_d4G1@images$slice1.008um@scale.factors$spot
spatial.factors = data.frame(ratio = conversion.factor, tol = spot.size/2)

d.spatial <- Compute_Cell_Distance(coordinates = spatial.locs, ratio = spatial.factors$ratio, tol = spatial.factors$tol)
min(d.spatial[d.spatial!=0]) # this value should approximately equal 8um for 10X VisiumHD data
#> [1] 7.999177
df=as.data.frame(as.matrix(d.spatial))

head(df)
#>                       s_008um_00110_00228-1 s_008um_00122_00239-1
#> s_008um_00110_00228-1                0.0000             130.22140
#> s_008um_00122_00239-1              130.2214               0.00000
#> s_008um_00125_00234-1              129.2325              46.64416
#> s_008um_00124_00223-1              118.9164             128.98896
#> s_008um_00131_00230-1              168.7433             101.81457
#> s_008um_00133_00224-1              186.7426             148.79694
#>                       s_008um_00125_00234-1 s_008um_00124_00223-1
#> s_008um_00110_00228-1             129.23247             118.91640
#> s_008um_00122_00239-1              46.64416             128.98896
#> s_008um_00125_00234-1               0.00000              88.35838
#> s_008um_00124_00223-1              88.35838               0.00000
#> s_008um_00131_00230-1              57.68334              79.19059
#> s_008um_00133_00224-1             102.44176              72.43592
#>                       s_008um_00131_00230-1 s_008um_00133_00224-1
#> s_008um_00110_00228-1             168.74335             186.74257
#> s_008um_00122_00239-1             101.81457             148.79694
#> s_008um_00125_00234-1              57.68334             102.44176
#> s_008um_00124_00223-1              79.19059              72.43592
#> s_008um_00131_00230-1               0.00000              50.59329
#> s_008um_00133_00224-1              50.59329               0.00000
#>                       s_008um_00108_00230-1 s_008um_00131_00235-1
#> s_008um_00110_00228-1              22.62545             177.07133
#> s_008um_00122_00239-1             133.13597              78.78292
#> s_008um_00125_00234-1             139.70066              48.65735
#> s_008um_00124_00223-1             139.69991             111.13323
#> s_008um_00131_00230-1             183.98123              39.99790
#> s_008um_00133_00224-1             205.65811              89.43763
#>                       s_008um_00126_00228-1 s_008um_00129_00228-1
#> s_008um_00110_00228-1             127.98695             151.98451
#> s_008um_00122_00239-1              93.63157             104.29940
#> s_008um_00125_00234-1              48.65934              57.68444
#> s_008um_00124_00223-1              43.07906              56.56471
#> s_008um_00131_00230-1              43.07750              22.62588
#> s_008um_00133_00224-1              64.49180              45.25096
#>                       s_008um_00108_00218-1 s_008um_00116_00225-1
#> s_008um_00110_00228-1              81.58021              53.66029
#> s_008um_00122_00239-1             201.89895             121.84584
#> s_008um_00125_00234-1             186.74895             101.81646
#> s_008um_00124_00223-1             134.09211              65.96289
#> s_008um_00131_00230-1             207.52061             126.47955
#> s_008um_00133_00224-1             205.65989             136.22113
#>                       s_008um_00118_00223-1 s_008um_00118_00228-1
#> s_008um_00110_00228-1              75.46458              63.99347
#> s_008um_00122_00239-1             131.93264              93.63268
#> s_008um_00125_00234-1             104.30116              73.75105
#> s_008um_00124_00223-1              47.99512              62.47635
#> s_008um_00131_00230-1             118.10879             105.21327
#> s_008um_00133_00224-1             120.25433             124.18062
#>                       s_008um_00125_00244-1 s_008um_00119_00222-1
#> s_008um_00110_00228-1             175.44198              86.52499
#> s_008um_00122_00239-1              46.64490             138.09440
#> s_008um_00125_00234-1              79.99574             107.32538
#> s_008um_00124_00223-1             168.18163              40.78823
#> s_008um_00131_00230-1             121.84418             115.36864
#> s_008um_00133_00224-1             172.31395             113.12600
#>                       s_008um_00109_00231-1 s_008um_00136_00235-1
#> s_008um_00110_00228-1              25.29662             215.38634
#> s_008um_00122_00239-1             122.10488             116.46974
#> s_008um_00125_00234-1             130.21791              88.35406
#> s_008um_00124_00223-1             135.98658             135.75528
#> s_008um_00131_00230-1             176.16362              56.56469
#> s_008um_00133_00224-1             199.97942              91.20938
#>                       s_008um_00127_00237-1 s_008um_00127_00234-1
#> s_008um_00110_00228-1             153.87020             144.20896
#> s_008um_00122_00239-1              43.07693              56.56363
#> s_008um_00125_00234-1              28.84269              15.99837
#> s_008um_00124_00223-1             114.53675              91.20938
#> s_008um_00131_00230-1              64.49338              45.25093
#> s_008um_00133_00224-1             114.53480              93.28840
#>                       s_008um_00120_00248-1 s_008um_00133_00244-1
#> s_008um_00110_00228-1             178.87549             224.12544
#> s_008um_00122_00239-1              73.75193              96.65595
#> s_008um_00125_00234-1             118.92084             102.44349
#> s_008um_00124_00223-1             202.53227             182.76874
#> s_008um_00131_00230-1             168.74758             113.13127
#> s_008um_00133_00224-1             218.34185             159.99158
#>                       s_008um_00137_00231-1 s_008um_00127_00245-1
#> s_008um_00110_00228-1             217.30767             192.31989
#> s_008um_00122_00239-1             135.98659              62.47797
#> s_008um_00125_00234-1              98.94433              89.43811
#> s_008um_00124_00223-1             122.10494             177.61974
#> s_008um_00131_00230-1              48.65736             124.18585
#> s_008um_00133_00224-1              64.49442             174.71195
#>                       s_008um_00136_00248-1 s_008um_00135_00229-1
#> s_008um_00110_00228-1              262.3998             200.13971
#> s_008um_00122_00239-1              133.1359             131.19763
#> s_008um_00125_00234-1              142.4270              89.43385
#> s_008um_00124_00223-1              221.8346             100.23143
#> s_008um_00131_00230-1              149.4446              32.98145
#> s_008um_00133_00224-1              193.4843              43.07905
#>                       s_008um_00117_00226-1 s_008um_00128_00219-1
#> s_008um_00110_00228-1              58.23487             160.98094
#> s_008um_00122_00239-1             111.42122             167.03465
#> s_008um_00125_00234-1              90.50351             122.36944
#> s_008um_00124_00223-1              60.92005              45.25097
#> s_008um_00131_00230-1             116.47090              91.20941
#> s_008um_00133_00224-1             128.98283              56.56473
#>                       s_008um_00124_00239-1 s_008um_00135_00222-1
#> s_008um_00110_00228-1             142.42537             205.65815
#> s_008um_00122_00239-1              15.99836             171.19390
#> s_008um_00125_00234-1              40.78977             124.95384
#> s_008um_00124_00223-1             127.99328              88.35382
#> s_008um_00131_00230-1              91.20673              71.54925
#> s_008um_00133_00224-1             139.93256              22.62549
#>                       s_008um_00117_00220-1 s_008um_00110_00226-1
#> s_008um_00110_00228-1              85.03412              15.99916
#> s_008um_00122_00239-1             157.16704             141.52508
#> s_008um_00125_00234-1             128.98884             135.98866
#> s_008um_00124_00223-1              60.92087             114.53072
#> s_008um_00131_00230-1             137.62671             171.00392
#> s_008um_00133_00224-1             131.92694             184.67533
#>                       s_008um_00123_00226-1 s_008um_00136_00223-1
#> s_008um_00110_00228-1             105.21267             211.78935
#> s_008um_00122_00239-1             104.30157             170.06826
#> s_008um_00125_00234-1              65.96633             124.44011
#> s_008um_00124_00223-1              25.29664              95.99027
#> s_008um_00131_00230-1              71.54813              68.81330
#> s_008um_00133_00224-1              81.57590              25.29565
#>                       s_008um_00112_00234-1 s_008um_00122_00241-1
#> s_008um_00110_00228-1              50.59381             141.52506
#> s_008um_00122_00239-1              89.43511              15.99915
#> s_008um_00125_00234-1             103.98937              60.92208
#> s_008um_00124_00223-1             130.21903             144.87817
#> s_008um_00131_00230-1             155.31580             113.69209
#> s_008um_00133_00224-1             186.05668             161.97544
#>                       s_008um_00131_00241-1 s_008um_00109_00220-1
#> s_008um_00110_00228-1             197.56957              64.49481
#> s_008um_00122_00239-1              73.74927             184.16286
#> s_008um_00125_00234-1              73.75158             170.07023
#> s_008um_00124_00223-1             154.49750             122.36469
#> s_008um_00131_00230-1              87.99536             193.31205
#> s_008um_00133_00224-1             136.93038             194.62946
#>                       s_008um_00121_00244-1 s_008um_00127_00226-1
#> s_008um_00110_00228-1             155.32256             136.92379
#> s_008um_00122_00239-1              40.78975             111.41985
#> s_008um_00125_00234-1              86.15692              65.96576
#> s_008um_00124_00223-1             169.69607              33.93883
#> s_008um_00131_00230-1             137.62643              45.25176
#> s_008um_00133_00224-1             186.57669              50.59129
#>                       s_008um_00114_00234-1 s_008um_00120_00231-1
#> s_008um_00110_00228-1              57.68540              83.51469
#> s_008um_00122_00239-1              75.46580              65.96630
#> s_008um_00125_00234-1              87.99101              46.64384
#> s_008um_00124_00223-1             118.91856              71.54921
#> s_008um_00131_00230-1             139.69953              88.35378
#> s_008um_00133_00224-1             171.75034             118.10700
#>                       s_008um_00132_00245-1 s_008um_00122_00219-1
#> s_008um_00110_00228-1             222.40636             119.98887
#> s_008um_00122_00239-1              93.28764             159.99163
#> s_008um_00125_00234-1             104.30108             122.37029
#> s_008um_00124_00223-1             187.26535              35.77515
#> s_008um_00131_00230-1             120.26012             113.69421
#> s_008um_00133_00224-1             168.18135              96.65605
#>                       s_008um_00133_00232-1 s_008um_00126_00227-1
#> s_008um_00110_00228-1             186.74369             128.23656
#> s_008um_00122_00239-1             104.29721             101.18650
#> s_008um_00125_00234-1              65.96288              56.56538
#> s_008um_00124_00223-1             101.81647              35.77514
#> s_008um_00131_00230-1              22.62588              46.64386
#> s_008um_00133_00224-1              63.99667              60.92007
#>                       s_008um_00122_00227-1 s_008um_00122_00238-1
#> s_008um_00110_00228-1              96.32281            124.954899
#> s_008um_00122_00239-1              95.99494              7.999574
#> s_008um_00125_00234-1              60.92293             39.996820
#> s_008um_00124_00223-1              35.77461            121.055224
#> s_008um_00131_00230-1              75.88773             96.324154
#> s_008um_00133_00224-1              91.20467            142.424543
#>                       s_008um_00115_00234-1 s_008um_00119_00233-1
#> s_008um_00110_00228-1              62.47802              82.35824
#> s_008um_00122_00239-1              68.81331              53.66266
#> s_008um_00125_00234-1              79.99182              48.65734
#> s_008um_00124_00223-1             113.69212              89.43650
#> s_008um_00131_00230-1             131.92573              98.94431
#> s_008um_00133_00224-1             164.71395             133.13382
#>                       s_008um_00118_00248-1 s_008um_00117_00231-1
#> s_008um_00110_00228-1             172.31604              60.92084
#> s_008um_00122_00239-1              78.78545              75.46744
#> s_008um_00125_00234-1             125.21096              68.34588
#> s_008um_00124_00223-1             205.66706              85.03412
#> s_008um_00131_00230-1             177.61483             112.27379
#> s_008um_00133_00224-1             226.39857             139.69996
#>                       s_008um_00119_00247-1 s_008um_00123_00234-1
#> s_008um_00110_00228-1             168.18112             114.53268
#> s_008um_00122_00239-1              68.34753              40.78977
#> s_008um_00125_00234-1             114.53466              15.99837
#> s_008um_00124_00223-1             196.11091              88.35809
#> s_008um_00131_00230-1             166.45621              71.54707
#> s_008um_00133_00224-1             215.39059             113.12735
#>                       s_008um_00132_00232-1 s_008um_00121_00243-1
#> s_008um_00110_00228-1             178.86806             148.79947
#> s_008um_00122_00239-1              97.64322              32.98284
#> s_008um_00125_00234-1              58.23488              78.78549
#> s_008um_00124_00223-1              96.32650             161.78085
#> s_008um_00131_00230-1              17.88756             131.19925
#> s_008um_00133_00224-1              64.49451             179.76417
#>                       s_008um_00136_00221-1 s_008um_00125_00247-1
#> s_008um_00110_00228-1             215.38443             193.64730
#> s_008um_00122_00239-1             182.41353              68.34837
#> s_008um_00125_00234-1             136.22398             103.99445
#> s_008um_00124_00223-1              97.31419             192.15657
#> s_008um_00131_00230-1              82.35919             144.21278
#> s_008um_00133_00224-1              33.93823             194.80031
#>                       s_008um_00130_00220-1 s_008um_00122_00243-1
#> s_008um_00110_00228-1             172.30784             153.66528
#> s_008um_00122_00239-1             164.91330              31.99829
#> s_008um_00125_00234-1             118.92101              75.88983
#> s_008um_00124_00223-1              53.66034             160.78917
#> s_008um_00131_00230-1              80.39494             126.48131
#> s_008um_00133_00224-1              39.99757             175.62318
#>                       s_008um_00135_00247-1 s_008um_00134_00230-1
#> s_008um_00110_00228-1              251.1862             192.64624
#> s_008um_00122_00239-1              122.1048             119.98884
#> s_008um_00125_00234-1              131.2015              78.78295
#> s_008um_00124_00223-1              211.1946              97.64495
#> s_008um_00131_00230-1              139.7068              23.99756
#> s_008um_00133_00224-1              184.6848              48.65965
#>                       s_008um_00127_00238-1 s_008um_00125_00231-1
#> s_008um_00110_00228-1             157.77183             122.36465
#> s_008um_00122_00239-1              40.78792              68.34759
#> s_008um_00125_00234-1              35.77510              23.99874
#> s_008um_00124_00223-1             122.37025              64.49480
#> s_008um_00131_00230-1              71.54918              48.65707
#> s_008um_00133_00224-1             121.84426              85.03359
#>                       s_008um_00108_00219-1 s_008um_00120_00220-1
#> s_008um_00110_00228-1              73.75264             102.44062
#> s_008um_00122_00239-1             195.29318             152.83199
#> s_008um_00125_00234-1             181.35968             118.92237
#> s_008um_00124_00223-1             131.92692              39.99701
#> s_008um_00131_00230-1             203.94338             118.92022
#> s_008um_00133_00224-1             203.94117             108.80175
#>                       s_008um_00125_00230-1 s_008um_00121_00231-1
#> s_008um_00110_00228-1             121.05001              91.20547
#> s_008um_00122_00239-1              75.88986              64.49475
#> s_008um_00125_00234-1              31.99832              39.99698
#> s_008um_00124_00223-1              56.56569              68.34764
#> s_008um_00131_00230-1              47.99512              80.39071
#> s_008um_00133_00224-1              79.99261             111.12877
#>                       s_008um_00126_00223-1 s_008um_00137_00242-1
#> s_008um_00110_00228-1             134.09066              243.2900
#> s_008um_00122_00239-1             131.93151              122.3646
#> s_008um_00125_00234-1              88.35809              115.3686
#> s_008um_00124_00223-1              15.99838              184.1628
#> s_008um_00131_00230-1              68.81446              107.3253
#> s_008um_00133_00224-1              56.56300              147.5052
#>                       s_008um_00114_00223-1 s_008um_00133_00246-1
#> s_008um_00110_00228-1              51.22086              233.6319
#> s_008um_00122_00239-1             143.10047              104.2989
#> s_008um_00125_00234-1             124.44234              115.3707
#> s_008um_00124_00223-1              79.99186              197.5749
#> s_008um_00131_00230-1             147.06525              128.9895
#> s_008um_00133_00224-1             152.19508              175.9907
#>                       s_008um_00117_00234-1 s_008um_00114_00231-1
#> s_008um_00110_00228-1              73.75105              39.99699
#> s_008um_00122_00239-1              56.56467              90.50349
#> s_008um_00125_00234-1              63.99346              91.20546
#> s_008um_00124_00223-1             104.29942             102.44061
#> s_008um_00131_00230-1             116.46975             136.22108
#> s_008um_00133_00224-1             150.92919             161.97117
#>                       s_008um_00135_00226-1 s_008um_00126_00236-1
#> s_008um_00110_00228-1             200.61833             143.09621
#> s_008um_00122_00239-1             147.06552              39.99626
#> s_008um_00125_00234-1             102.44064              17.88755
#> s_008um_00124_00223-1              91.20551             105.21824
#> s_008um_00131_00230-1              45.25096              62.47689
#> s_008um_00133_00224-1              22.62589             111.13147
#>                       s_008um_00133_00248-1 s_008um_00130_00233-1
#> s_008um_00110_00228-1              243.8185             164.90860
#> s_008um_00122_00239-1              113.6930              79.99255
#> s_008um_00125_00234-1              128.9887              40.78793
#> s_008um_00124_00223-1              212.5541              93.28989
#> s_008um_00131_00230-1              144.8787              25.29663
#> s_008um_00133_00224-1              191.9899              75.88993
#>                       s_008um_00107_00218-1 s_008um_00133_00221-1
#> s_008um_00110_00228-1               83.5182             192.31331
#> s_008um_00122_00239-1              206.4434             168.74772
#> s_008um_00125_00234-1              192.6519             122.10570
#> s_008um_00124_00223-1              141.7472              73.74877
#> s_008um_00131_00230-1              214.6444              73.75208
#> s_008um_00133_00224-1              213.4463              23.99876
#>                       s_008um_00118_00227-1 s_008um_00131_00227-1
#> s_008um_00110_00228-1              64.49138             168.17311
#> s_008um_00122_00239-1             101.18761             119.99051
#> s_008um_00125_00234-1              79.19057              73.75029
#> s_008um_00124_00223-1              57.68335              64.49280
#> s_008um_00131_00230-1             106.72314              23.99875
#> s_008um_00133_00224-1             122.36384              28.84224
#>                       s_008um_00109_00221-1 s_008um_00123_00246-1
#> s_008um_00110_00228-1              56.56569             177.61797
#> s_008um_00122_00239-1             177.61805              56.56560
#> s_008um_00125_00234-1             164.91217              97.31859
#> s_008um_00124_00223-1             121.05005             184.16394
#> s_008um_00131_00230-1             190.14106             143.09830
#> s_008um_00133_00224-1             193.47511             193.31558
#>                       s_008um_00133_00241-1 s_008um_00129_00245-1
#> s_008um_00110_00228-1             211.34012             203.94626
#> s_008um_00122_00239-1              89.43400              73.75100
#> s_008um_00125_00234-1              85.03506              93.63263
#> s_008um_00124_00223-1             160.98802             180.47899
#> s_008um_00131_00230-1              89.43814             121.05516
#> s_008um_00133_00224-1             135.99286             171.01059
#>                       s_008um_00136_00232-1 s_008um_00120_00241-1
#> s_008um_00110_00228-1             210.42652             131.20159
#> s_008um_00122_00239-1             125.20736              22.62544
#> s_008um_00125_00234-1              89.43347              68.81320
#> s_008um_00124_00223-1             119.99099             147.50403
#> s_008um_00131_00230-1              43.07750             124.44001
#> s_008um_00133_00224-1              68.34846             171.19385
#>                       s_008um_00128_00247-1 s_008um_00113_00221-1
#> s_008um_00110_00228-1             209.36598              60.92213
#> s_008um_00122_00239-1              79.99501             160.98805
#> s_008um_00125_00234-1             106.72779             141.52513
#> s_008um_00124_00223-1             194.63844              89.43406
#> s_008um_00131_00230-1             138.09345             160.98330
#> s_008um_00133_00224-1             188.28657             161.77417
#>                       s_008um_00135_00233-1 s_008um_00136_00222-1
#> s_008um_00110_00228-1             203.94109             213.44460
#> s_008um_00122_00239-1             114.53108             176.16742
#> s_008um_00125_00234-1              80.39071             130.21967
#> s_008um_00124_00223-1             118.92019              96.32288
#> s_008um_00131_00230-1              39.99699              75.46628
#> s_008um_00133_00224-1              73.75262              28.84170
#>                       s_008um_00124_00247-1 s_008um_00117_00222-1
#> s_008um_00110_00228-1             188.79515              73.74971
#> s_008um_00122_00239-1              65.96625             141.75307
#> s_008um_00125_00234-1             104.30150             115.37083
#> s_008um_00124_00223-1             191.98985              56.56299
#> s_008um_00131_00230-1             147.06841             128.98560
#> s_008um_00133_00224-1             197.57248             128.98341
#>                       s_008um_00133_00218-1 s_008um_00113_00225-1
#> s_008um_00110_00228-1             200.61884              33.93819
#> s_008um_00122_00239-1             189.63898             133.13872
#> s_008um_00125_00234-1             143.09847             119.99097
#> s_008um_00124_00223-1              82.35704              89.43347
#> s_008um_00131_00230-1              97.31876             149.43835
#> s_008um_00133_00224-1              47.99753             160.18346
#>                       s_008um_00123_00223-1 s_008um_00118_00234-1
#> s_008um_00110_00228-1            111.415773              79.99397
#> s_008um_00122_00239-1            128.242853              51.22176
#> s_008um_00125_00234-1             89.438193              55.99428
#> s_008um_00124_00223-1              7.999187             100.23256
#> s_008um_00131_00230-1             85.035117             108.80057
#> s_008um_00133_00224-1             80.391031             144.20836
#>                       s_008um_00129_00246-1 s_008um_00136_00225-1
#> s_008um_00110_00228-1             209.36543             209.35843
#> s_008um_00122_00239-1              79.19051             158.37827
#> s_008um_00125_00234-1             101.18755             113.69106
#> s_008um_00124_00223-1             188.28800              97.31474
#> s_008um_00131_00230-1             128.98890              56.56370
#> s_008um_00133_00224-1             178.87516              25.29592
#>                       s_008um_00126_00221-1 s_008um_00107_00224-1
#> s_008um_00110_00228-1             139.69994              39.99756
#> s_008um_00122_00239-1             147.50407             169.69407
#> s_008um_00125_00234-1             104.30163             164.71650
#> s_008um_00124_00223-1              22.62548             136.22109
#> s_008um_00131_00230-1              82.36043             197.89034
#> s_008um_00133_00224-1              60.92088             207.97884
#>                       s_008um_00129_00234-1 s_008um_00124_00238-1
#> s_008um_00110_00228-1             159.38416             137.62665
#> s_008um_00122_00239-1              68.81212              17.88676
#> s_008um_00125_00234-1              31.99674              32.98286
#> s_008um_00124_00223-1              96.65916             119.99371
#> s_008um_00131_00230-1              35.77460              85.03410
#> s_008um_00133_00224-1              86.15702             133.13654
#>                       s_008um_00106_00239-1 s_008um_00119_00235-1
#> s_008um_00110_00228-1              93.63152              91.20724
#> s_008um_00122_00239-1             127.98686              39.99752
#> s_008um_00125_00234-1             157.15873              48.65705
#> s_008um_00124_00223-1             192.64825             103.99312
#> s_008um_00131_00230-1             212.54349             103.98948
#> s_008um_00133_00224-1             247.07084             142.42288
#>                       s_008um_00124_00222-1 s_008um_00134_00226-1
#> s_008um_00110_00228-1            121.840082             192.64567
#> s_008um_00122_00239-1            136.930378             141.52252
#> s_008um_00125_00234-1             96.327843              96.32420
#> s_008um_00124_00223-1              7.999587              83.51473
#> s_008um_00131_00230-1             85.035680              39.99686
#> s_008um_00133_00224-1             73.749329              17.88757
#>                       s_008um_00124_00244-1 s_008um_00120_00240-1
#> s_008um_00110_00228-1             170.07125             124.95601
#> s_008um_00122_00239-1              43.07900              17.88675
#> s_008um_00125_00234-1              80.39454              62.47685
#> s_008um_00124_00223-1             167.99115             139.70572
#> s_008um_00131_00230-1             125.21103             118.91798
#> s_008um_00133_00224-1             175.44181             164.91085
#>                       s_008um_00123_00235-1 s_008um_00135_00231-1
#> s_008um_00110_00228-1             118.10875             201.41490
#> s_008um_00122_00239-1              32.98286             122.10291
#> s_008um_00125_00234-1              17.88676              83.51387
#> s_008um_00124_00223-1              96.32754             108.80351
#> s_008um_00131_00230-1              75.46459              32.98173
#> s_008um_00133_00224-1             118.91860              58.23791
#>                       s_008um_00131_00232-1 s_008um_00133_00239-1
#> s_008um_00110_00228-1             171.00390             203.94329
#> s_008um_00122_00239-1              91.20561              87.99101
#> s_008um_00125_00234-1              50.59126              75.46581
#> s_008um_00124_00223-1              91.20838             146.85217
#> s_008um_00131_00230-1              15.99916              73.75258
#> s_008um_00133_00224-1              65.96579             119.99371
#>                       s_008um_00135_00221-1 s_008um_00133_00234-1
#> s_008um_00110_00228-1             207.67073             190.13989
#> s_008um_00122_00239-1             177.61500              96.65465
#> s_008um_00125_00234-1             131.19937              63.99348
#> s_008um_00124_00223-1              89.43352             113.69418
#> s_008um_00131_00230-1              78.78562              35.77512
#> s_008um_00133_00224-1              28.84225              79.99583
#>                       s_008um_00133_00237-1 s_008um_00114_00236-1
#> s_008um_00110_00228-1             197.56779              71.55023
#> s_008um_00122_00239-1              89.43344              68.34586
#> s_008um_00125_00234-1              68.34588              89.43342
#> s_008um_00124_00223-1             133.13874             131.19929
#> s_008um_00131_00230-1              58.23788             144.20729
#> s_008um_00133_00224-1             103.99456             179.76037
#>                       s_008um_00115_00225-1 s_008um_00124_00245-1
#> s_008um_00110_00228-1              46.64308             176.17048
#> s_008um_00122_00239-1             125.21291              50.59377
#> s_008um_00125_00234-1             107.62139              88.35800
#> s_008um_00124_00223-1              73.74874             175.99072
#> s_008um_00131_00230-1             134.09208             132.41445
#> s_008um_00133_00224-1             144.20727             182.76632
#>                       s_008um_00118_00244-1 s_008um_00128_00237-1
#> s_008um_00110_00228-1             143.10042             160.98324
#> s_008um_00122_00239-1              51.22081              50.59124
#> s_008um_00125_00234-1              97.64482              33.93881
#> s_008um_00124_00223-1             174.71192             116.47579
#> s_008um_00131_00230-1             152.82680              60.92211
#> s_008um_00133_00224-1             199.98415             111.41990
#>                       s_008um_00111_00222-1 s_008um_00130_00248-1
#> s_008um_00110_00228-1              48.65935              226.2587
#> s_008um_00122_00239-1             161.97815               96.3264
#> s_008um_00125_00234-1             147.50213              118.9222
#> s_008um_00124_00223-1             104.29681              205.6688
#> s_008um_00131_00230-1             172.31001              144.2142
#> s_008um_00133_00224-1             176.70818              193.4834
#>                       s_008um_00132_00238-1 s_008um_00126_00238-1
#> s_008um_00110_00228-1             193.31197             150.93163
#> s_008um_00122_00239-1              80.39068              32.98142
#> s_008um_00125_00234-1              64.49277              32.98315
#> s_008um_00124_00223-1             135.99241             121.05581
#> s_008um_00131_00230-1              64.49476              75.46621
#> s_008um_00133_00224-1             112.27930             125.21111
#>                       s_008um_00129_00244-1 s_008um_00118_00230-1
#> s_008um_00110_00228-1             198.70143              65.96344
#> s_008um_00122_00239-1              68.81329              78.78660
#> s_008um_00125_00234-1              86.15802              64.49278
#> s_008um_00124_00223-1             172.68742              73.75029
#> s_008um_00131_00230-1             113.13070             103.98941
#> s_008um_00133_00224-1             163.15916             129.23089
#>                       s_008um_00127_00230-1 s_008um_00106_00225-1
#> s_008um_00110_00228-1             136.92436              39.99699
#> s_008um_00122_00239-1              82.35909             170.07018
#> s_008um_00125_00234-1              35.77459             168.17594
#> s_008um_00124_00223-1              60.92295             144.87119
#> s_008um_00131_00230-1              31.99674             203.94111
#> s_008um_00133_00224-1              67.87643             216.12597
#>                       s_008um_00128_00226-1 s_008um_00110_00231-1
#> s_008um_00110_00228-1             144.87119              23.99874
#> s_008um_00122_00239-1             114.53475             115.36858
#> s_008um_00125_00234-1              68.34763             122.36463
#> s_008um_00124_00223-1              39.99700             128.98352
#> s_008um_00131_00230-1              39.99755             168.17308
#> s_008um_00133_00224-1              43.07698             192.31328
#>                       s_008um_00128_00221-1 s_008um_00107_00219-1
#> s_008um_00110_00228-1             154.48999              75.89077
#> s_008um_00122_00239-1             151.77980             199.98773
#> s_008um_00125_00234-1             106.72706             187.43242
#> s_008um_00124_00223-1              35.77356             139.70073
#> s_008um_00131_00230-1              75.89076             211.18787
#> s_008um_00133_00224-1              46.64387             211.79081
#>                       s_008um_00116_00230-1 s_008um_00131_00225-1
#> s_008um_00110_00228-1              50.59181             169.68808
#> s_008um_00122_00239-1              86.52808             133.13652
#> s_008um_00125_00234-1              78.78400              86.52667
#> s_008um_00124_00223-1              85.03356              58.23546
#> s_008um_00131_00230-1             119.98777              39.99792
#> s_008um_00133_00224-1             144.20735              17.88678
#>                       s_008um_00130_00225-1 s_008um_00137_00235-1
#> s_008um_00110_00228-1             161.77325             223.12015
#> s_008um_00122_00239-1             128.98677             124.18057
#> s_008um_00125_00234-1              82.35914              96.32312
#> s_008um_00124_00223-1              50.59183             141.52455
#> s_008um_00131_00230-1              40.79010              62.47745
#> s_008um_00133_00224-1              25.29565              93.63271
#>                       s_008um_00131_00244-1 s_008um_00130_00234-1
#> s_008um_00110_00228-1             211.19017             167.02939
#> s_008um_00122_00239-1              82.35820              75.46456
#> s_008um_00125_00234-1              93.28981              39.99592
#> s_008um_00124_00223-1             177.07832             100.23411
#> s_008um_00131_00230-1             111.99407              32.98288
#> s_008um_00133_00224-1             160.78918              83.51734
#>                       s_008um_00137_00221-1 s_008um_00115_00226-1
#> s_008um_00110_00228-1             223.11824              43.07694
#> s_008um_00122_00239-1             187.43073             118.11196
#> s_008um_00125_00234-1             141.52260             102.44244
#> s_008um_00124_00223-1             105.21275              75.88690
#> s_008um_00131_00230-1              86.52672             131.92690
#> s_008um_00133_00224-1              39.99633             144.87123
#>                       s_008um_00132_00239-1 s_008um_00120_00223-1
#> s_008um_00110_00228-1             196.75728              89.43383
#> s_008um_00122_00239-1              79.99182             128.98954
#> s_008um_00125_00234-1              68.81331              96.65916
#> s_008um_00124_00223-1             143.10047              31.99675
#> s_008um_00131_00230-1              72.43936             104.29898
#> s_008um_00133_00224-1             120.25990             104.29683
#>                       s_008um_00130_00245-1 s_008um_00120_00242-1
#> s_008um_00110_00228-1             209.97526             137.62884
#> s_008um_00122_00239-1              79.99392              28.84219
#> s_008um_00125_00234-1              96.65908              75.46617
#> s_008um_00124_00223-1             182.41867             155.32282
#> s_008um_00131_00230-1             120.25983             130.21956
#> s_008um_00133_00224-1             169.69609             177.61494
#>                       s_008um_00120_00230-1 s_008um_00137_00222-1
#> s_008um_00110_00228-1              81.57643             221.24623
#> s_008um_00122_00239-1              73.75258             181.35751
#> s_008um_00125_00234-1              51.22122             135.75285
#> s_008um_00124_00223-1              64.49340             104.29656
#> s_008um_00131_00230-1              87.99104              79.99374
#> s_008um_00133_00224-1             114.53113              35.77357
#>                       s_008um_00127_00218-1 s_008um_00135_00228-1
#> s_008um_00110_00228-1             157.76937             199.97963
#> s_008um_00122_00239-1             172.68608             136.22279
#> s_008um_00125_00234-1             128.98903              93.28622
#> s_008um_00124_00223-1              46.64423              96.65603
#> s_008um_00131_00230-1             101.18769              35.77355
#> s_008um_00133_00224-1              67.87767              35.77513
#>                       s_008um_00112_00226-1 s_008um_00123_00247-1
#> s_008um_00110_00228-1              22.62546              184.1628
#> s_008um_00122_00239-1             131.20161               64.4947
#> s_008um_00125_00234-1             122.10491              105.2175
#> s_008um_00124_00223-1              98.94432              192.1563
#> s_008um_00131_00230-1             155.31698              150.2960
#> s_008um_00133_00224-1             168.74281              200.6255
#>                       s_008um_00119_00225-1 s_008um_00137_00239-1
#> s_008um_00110_00228-1              75.88687             233.21741
#> s_008um_00122_00239-1             114.53673             119.98774
#> s_008um_00125_00234-1              86.52811             103.99082
#> s_008um_00124_00223-1              43.07696             164.91380
#> s_008um_00131_00230-1             103.99085              86.52808
#> s_008um_00133_00224-1             112.27383             124.18704
#>                       s_008um_00106_00218-1 s_008um_00119_00226-1
#> s_008um_00110_00228-1              86.15813              73.74871
#> s_008um_00122_00239-1             211.19305             106.72786
#> s_008um_00125_00234-1             198.70155              79.99509
#> s_008um_00124_00223-1             149.43838              46.64311
#> s_008um_00131_00230-1             221.82789             101.18364
#> s_008um_00133_00224-1             221.24797             113.12542
#>                       s_008um_00127_00242-1 s_008um_00132_00243-1
#> s_008um_00110_00228-1             176.16883             212.99982
#> s_008um_00122_00239-1              46.64382              86.15495
#> s_008um_00125_00234-1              65.96628              91.20831
#> s_008um_00124_00223-1             153.87523             172.31612
#> s_008um_00131_00230-1             101.18649             104.30184
#> s_008um_00133_00224-1             151.77978             152.20221
#>                       s_008um_00121_00222-1 s_008um_00132_00242-1
#> s_008um_00110_00228-1             100.22986             208.59787
#> s_008um_00122_00239-1             136.22807              83.51467
#> s_008um_00125_00234-1             101.18766              85.03561
#> s_008um_00124_00223-1              25.29592             164.91540
#> s_008um_00131_00230-1             102.44247              96.32778
#> s_008um_00133_00224-1              97.31474             144.21431
#>                       s_008um_00122_00245-1 s_008um_00122_00228-1
#> s_008um_00110_00228-1             166.45912              95.99020
#> s_008um_00122_00239-1              47.99743              87.99536
#> s_008um_00125_00234-1              91.20844              53.66268
#> s_008um_00124_00223-1             176.71609              43.07851
#> s_008um_00131_00230-1             139.93247              73.74931
#> s_008um_00133_00224-1             189.63888              93.62809
#>                       s_008um_00112_00229-1 s_008um_00111_00223-1
#> s_008um_00110_00228-1              17.88703               40.7898
#> s_008um_00122_00239-1             113.12937              155.3226
#> s_008um_00125_00234-1             111.41713              142.4254
#> s_008um_00124_00223-1             107.32060              103.9894
#> s_008um_00131_00230-1             152.19503              169.5016
#> s_008um_00133_00224-1             172.67844              176.1640
#>                       s_008um_00118_00242-1 s_008um_00107_00221-1
#> s_008um_00110_00228-1             128.98876              60.92296
#> s_008um_00122_00239-1              39.99625             187.43406
#> s_008um_00125_00234-1              85.03405             177.61531
#> s_008um_00124_00223-1             159.38892             136.92439
#> s_008um_00131_00230-1             141.52190             205.03771
#> s_008um_00133_00224-1             187.43065             209.35933
#>                       s_008um_00132_00234-1 s_008um_00108_00221-1
#> s_008um_00110_00228-1             182.41094              58.23792
#> s_008um_00122_00239-1              89.43381             182.41673
#> s_008um_00125_00234-1              55.99429             171.19469
#> s_008um_00124_00223-1             108.80516             128.98339
#> s_008um_00131_00230-1              32.98316             197.56785
#> s_008um_00133_00224-1              80.39463             201.41496
#>                       s_008um_00112_00224-1 s_008um_00129_00218-1
#> s_008um_00110_00228-1              35.77459             171.75037
#> s_008um_00122_00239-1             144.21350             177.07646
#> s_008um_00125_00234-1             131.19997             131.93158
#> s_008um_00124_00223-1              96.32284              56.56371
#> s_008um_00131_00230-1             159.38420              97.31932
#> s_008um_00133_00224-1             167.98292              57.68544
#>                       s_008um_00113_00218-1 s_008um_00126_00241-1
#> s_008um_00110_00228-1              83.51734             164.91210
#> s_008um_00122_00239-1             182.76881              35.77404
#> s_008um_00125_00234-1             159.99022              56.56563
#> s_008um_00124_00223-1              96.65604             144.87875
#> s_008um_00131_00230-1             173.05298              96.65779
#> s_008um_00133_00224-1             167.02948             147.06850
#>                       s_008um_00131_00247-1 s_008um_00131_00226-1
#> s_008um_00110_00228-1             226.54076             168.74278
#> s_008um_00122_00239-1              96.32585             126.48136
#> s_008um_00125_00234-1             114.53627              79.99370
#> s_008um_00124_00223-1             199.98965              60.92087
#> s_008um_00131_00230-1             135.99278              31.99833
#> s_008um_00133_00224-1             184.68424              22.62548
#>                       s_008um_00107_00238-1 s_008um_00108_00240-1
#> s_008um_00110_00228-1              83.51725              97.31861
#> s_008um_00122_00239-1             120.25421             112.27371
#> s_008um_00125_00234-1             147.49736             144.20721
#> s_008um_00124_00223-1             181.35627             186.74596
#> s_008um_00131_00230-1             202.36495             200.61867
#> s_008um_00133_00224-1             236.21387             237.43033
#>                       s_008um_00133_00219-1 s_008um_00137_00238-1
#> s_008um_00110_00228-1             197.56542             230.31813
#> s_008um_00122_00239-1             182.59036             120.25397
#> s_008um_00125_00234-1             135.99042             101.18361
#> s_008um_00124_00223-1              78.78300             158.78521
#> s_008um_00131_00230-1              89.43767              79.99506
#> s_008um_00133_00224-1              39.99794             116.47578
#>                       s_008um_00111_00218-1 s_008um_00120_00244-1
#> s_008um_00110_00228-1              80.39464             150.93487
#> s_008um_00122_00239-1             189.64181              43.07845
#> s_008um_00125_00234-1             170.07136              89.43642
#> s_008um_00124_00223-1             111.41719             171.01057
#> s_008um_00131_00230-1             186.57546             142.42446
#> s_008um_00133_00224-1             182.41102             190.81532
#>                       s_008um_00121_00220-1 s_008um_00131_00236-1
#> s_008um_00110_00228-1             108.80160             179.76152
#> s_008um_00122_00239-1             152.20254              75.88687
#> s_008um_00125_00234-1             116.47582              50.59181
#> s_008um_00124_00223-1              33.93884             118.11199
#> s_008um_00131_00230-1             113.12943              47.99748
#> s_008um_00133_00224-1             101.18367              97.31870
#>                       s_008um_00133_00230-1 s_008um_00131_00240-1
#> s_008um_00110_00228-1             184.67588             193.47831
#> s_008um_00122_00239-1             113.69100              72.43586
#> s_008um_00125_00234-1              71.54708              67.87761
#> s_008um_00124_00223-1              91.20727             147.07038
#> s_008um_00131_00230-1              15.99837              79.99578
#> s_008um_00133_00224-1              47.99751             128.98898
#>                       s_008um_00131_00239-1 s_008um_00133_00227-1
#> s_008um_00110_00228-1             189.63640             184.15494
#> s_008um_00122_00239-1              71.99264             130.21960
#> s_008um_00125_00234-1              62.47744              85.03357
#> s_008um_00124_00223-1             139.70649              78.78404
#> s_008um_00131_00230-1              71.99621              28.84223
#> s_008um_00133_00224-1             121.05524              23.99876
#>                       s_008um_00133_00235-1 s_008um_00117_00238-1
#> s_008um_00110_00228-1             192.31521              97.64656
#> s_008um_00122_00239-1              93.62803              40.78820
#> s_008um_00125_00234-1              64.49168              71.54703
#> s_008um_00124_00223-1             119.99264             132.41450
#> s_008um_00131_00230-1              43.07903             128.98350
#> s_008um_00133_00224-1              87.99541             170.06711
#>                       s_008um_00122_00234-1 s_008um_00131_00222-1
#> s_008um_00110_00228-1             107.32216             174.70467
#> s_008um_00122_00239-1              39.99788             153.87219
#> s_008um_00125_00234-1              23.99755             107.32383
#> s_008um_00124_00223-1              89.43762              56.56272
#> s_008um_00131_00230-1              78.78294              63.99668
#> s_008um_00133_00224-1             118.91804              22.62589
#>                       s_008um_00132_00244-1 s_008um_00134_00223-1
#> s_008um_00110_00228-1             217.60690             196.10215
#> s_008um_00122_00239-1              89.43510             159.98738
#> s_008um_00125_00234-1              97.64652             113.69217
#> s_008um_00124_00223-1             179.76814              79.99189
#> s_008um_00131_00230-1             112.27953              60.92216
#> s_008um_00133_00224-1             160.19128              11.31274
#>                       s_008um_00119_00224-1 s_008um_00127_00243-1
#> s_008um_00110_00228-1              78.78293             181.35958
#> s_008um_00122_00239-1             122.37024              51.22119
#> s_008um_00125_00234-1              93.28988              73.75255
#> s_008um_00124_00223-1              40.78794             161.78173
#> s_008um_00131_00230-1             107.32219             108.80499
#> s_008um_00133_00224-1             111.98863             159.38895
#>                       s_008um_00123_00236-1 s_008um_00131_00238-1
#> s_008um_00110_00228-1             122.10490             186.05929
#> s_008um_00122_00239-1              25.29661              72.43557
#> s_008um_00125_00234-1              22.62546              57.68429
#> s_008um_00124_00223-1             104.30160             132.41638
#> s_008um_00131_00230-1              79.99257              63.99663
#> s_008um_00133_00224-1             124.95381             113.13077
#>                       s_008um_00121_00240-1 s_008um_00123_00218-1
#> s_008um_00110_00228-1             130.22195             131.19766
#> s_008um_00122_00239-1              11.31272             168.18141
#> s_008um_00125_00234-1              57.68440             128.98961
#> s_008um_00124_00223-1             138.09352              40.79012
#> s_008um_00131_00230-1             113.12729             115.37086
#> s_008um_00133_00224-1             159.98736              93.28775
#>                       s_008um_00134_00233-1 s_008um_00136_00244-1
#> s_008um_00110_00228-1             196.10354              244.2098
#> s_008um_00122_00239-1             107.32058              118.9177
#> s_008um_00125_00234-1              72.43560              118.9201
#> s_008um_00124_00223-1             113.12941              193.4832
#> s_008um_00131_00230-1              33.93881              118.9223
#> s_008um_00133_00224-1              72.43941              161.7817
#>                       s_008um_00124_00242-1 s_008um_00132_00233-1
#> s_008um_00110_00228-1             158.38110             180.47098
#> s_008um_00122_00239-1              28.84268              93.28617
#> s_008um_00125_00234-1              64.49444              56.56269
#> s_008um_00124_00223-1             151.99200             102.44357
#> s_008um_00131_00230-1             111.13141              25.29691
#> s_008um_00133_00224-1             160.98567              72.43912
#>                       s_008um_00115_00235-1 s_008um_00128_00243-1
#> s_008um_00110_00228-1              68.81444             187.43232
#> s_008um_00122_00239-1              64.49276              57.68427
#> s_008um_00125_00234-1              80.39068              75.89068
#> s_008um_00124_00223-1             119.99051             163.16030
#> s_008um_00131_00230-1             134.09064             106.72698
#> s_008um_00133_00224-1             168.74389             157.16559
#>                       s_008um_00118_00233-1 s_008um_00134_00246-1
#> s_008um_00110_00228-1              75.46582              239.9818
#> s_008um_00122_00239-1              57.68538              111.1304
#> s_008um_00125_00234-1              56.56297              119.9925
#> s_008um_00124_00223-1              93.28837              200.6282
#> s_008um_00131_00230-1             106.72227              130.2239
#> s_008um_00133_00224-1             139.92932              176.1726
#>                       s_008um_00111_00232-1 s_008um_00114_00222-1
#> s_008um_00110_00228-1              32.98316              57.68443
#> s_008um_00122_00239-1             104.29893             150.29819
#> s_008um_00125_00234-1             113.12593             130.22200
#> s_008um_00124_00223-1             126.47915              80.39102
#> s_008um_00131_00230-1             160.78139             150.29348
#> s_008um_00133_00224-1             187.25611             152.82463
#>                       s_008um_00106_00220-1 s_008um_00127_00235-1
#> s_008um_00110_00228-1              71.55028             147.06521
#> s_008um_00122_00239-1             198.70319              51.22028
#> s_008um_00125_00234-1             188.79251              17.88703
#> s_008um_00124_00223-1             145.97208              98.94950
#> s_008um_00131_00230-1             215.38751              51.22086
#> s_008um_00133_00224-1             218.33613             100.23258
#>                       s_008um_00123_00248-1 s_008um_00109_00218-1
#> s_008um_00110_00228-1              190.8185              80.39494
#> s_008um_00122_00239-1               72.4393             197.57401
#> s_008um_00125_00234-1              113.1306             181.00708
#> s_008um_00124_00223-1              200.1492             126.47958
#> s_008um_00131_00230-1              157.5710             200.46287
#> s_008um_00133_00224-1              207.9861             197.89041
#>                       s_008um_00135_00241-1 s_008um_00119_00219-1
#> s_008um_00110_00228-1             225.40509             101.81460
#> s_008um_00122_00239-1             105.21322             161.78178
#> s_008um_00125_00234-1              97.64489             129.23716
#> s_008um_00124_00223-1             168.75042              51.22125
#> s_008um_00131_00230-1              93.63266             130.22147
#> s_008um_00133_00224-1             136.93095             118.91784
#>                       s_008um_00134_00247-1 s_008um_00135_00225-1
#> s_008um_00110_00228-1              244.8654             201.41406
#> s_008um_00122_00239-1              115.3685             152.82689
#> s_008um_00125_00234-1              126.4834             107.61947
#> s_008um_00124_00223-1              207.9888              89.43407
#> s_008um_00131_00230-1              138.0943              51.22090
#> s_008um_00133_00224-1              184.1642              17.88704
#>                       s_008um_00115_00232-1 s_008um_00108_00225-1
#> s_008um_00110_00228-1              51.22122              28.84271
#> s_008um_00122_00239-1              79.19055             158.38113
#> s_008um_00125_00234-1              81.57642             153.87022
#> s_008um_00124_00223-1             101.81459             128.98279
#> s_008um_00131_00230-1             128.98278             188.27959
#> s_008um_00133_00224-1             157.56591             200.13944
#>                       s_008um_00128_00227-1 s_008um_00121_00237-1
#> s_008um_00110_00228-1             144.20723             113.69304
#> s_008um_00122_00239-1             107.32377              17.88755
#> s_008um_00125_00234-1              60.92212              39.99627
#> s_008um_00124_00223-1              45.25177             114.53589
#> s_008um_00131_00230-1              33.93882              97.64323
#> s_008um_00133_00224-1              46.64313             141.52254
#>                       s_008um_00107_00220-1 s_008um_00120_00238-1
#> s_008um_00110_00228-1              68.34848             113.12937
#> s_008um_00122_00239-1             193.64740              17.88702
#> s_008um_00125_00234-1             182.41453              51.22028
#> s_008um_00124_00223-1             138.08801             124.18591
#> s_008um_00131_00230-1             207.98172             108.80157
#> s_008um_00133_00224-1             210.42658             152.82689
#>                       s_008um_00125_00228-1 s_008um_00125_00225-1
#> s_008um_00110_00228-1             119.98776             122.36379
#> s_008um_00122_00239-1              91.20849             114.53587
#> s_008um_00125_00234-1              47.99748              71.99623
#> s_008um_00124_00223-1              40.79010              17.88757
#> s_008um_00131_00230-1              50.59182              62.47747
#> s_008um_00133_00224-1              71.54710              64.49142
#>                       s_008um_00127_00222-1 s_008um_00125_00220-1
#> s_008um_00110_00228-1             144.20733             135.98661
#> s_008um_00122_00239-1             141.75167             153.87440
#> s_008um_00125_00234-1              97.31871             111.99417
#> s_008um_00124_00223-1              25.29564              25.29665
#> s_008um_00131_00230-1              71.55027              93.28991
#> s_008um_00133_00224-1              50.59184              71.54815
#>                       s_008um_00114_00233-1 s_008um_00108_00227-1
#> s_008um_00110_00228-1              51.22178              17.88703
#> s_008um_00122_00239-1              79.99395             147.50208
#> s_008um_00125_00234-1              88.35404             147.06521
#> s_008um_00124_00223-1             113.12732             131.92575
#> s_008um_00131_00230-1             138.08710             185.54029
#> s_008um_00133_00224-1             168.17358             201.41405
#>                       s_008um_00137_00247-1 s_008um_00137_00223-1
#> s_008um_00110_00228-1              264.1008             219.64979
#> s_008um_00122_00239-1              135.9886             175.43887
#> s_008um_00125_00234-1              141.5250             130.21911
#> s_008um_00124_00223-1              218.3452             103.98946
#> s_008um_00131_00230-1              144.2144              73.75033
#> s_008um_00133_00224-1              186.7523              32.98146
#>                       s_008um_00117_00239-1 s_008um_00120_00219-1
#> s_008um_00110_00228-1             104.30113             107.61944
#> s_008um_00122_00239-1              39.99590             160.78981
#> s_008um_00125_00234-1              75.46454             126.48459
#> s_008um_00124_00223-1             139.70460              45.25178
#> s_008um_00131_00230-1             133.13375             124.44238
#> s_008um_00133_00224-1             175.43827             111.41720
#>                       s_008um_00118_00220-1 s_008um_00121_00224-1
#> s_008um_00110_00228-1              90.50186              93.62804
#> s_008um_00122_00239-1             155.32402             120.26017
#> s_008um_00125_00234-1             125.21295              86.15809
#> s_008um_00124_00223-1              53.66111              25.29564
#> s_008um_00131_00230-1             131.20000              93.28772
#> s_008um_00133_00224-1             124.18177              95.99025
#>                       s_008um_00109_00223-1 s_008um_00137_00243-1
#> s_008um_00110_00228-1               40.7901              247.0747
#> s_008um_00122_00239-1              164.9138              124.1817
#> s_008um_00125_00234-1              155.3199              119.9909
#> s_008um_00124_00223-1              119.9878              190.8185
#> s_008um_00131_00230-1              184.6774              114.5363
#> s_008um_00133_00224-1              192.1472              155.3240
#>                       s_008um_00123_00227-1 s_008um_00118_00236-1
#> s_008um_00110_00228-1             104.29648              90.50350
#> s_008um_00122_00239-1              96.32750              39.99697
#> s_008um_00125_00234-1              58.23789              58.23486
#> s_008um_00124_00223-1              32.98289             114.53477
#> s_008um_00131_00230-1              68.34590             114.53108
#> s_008um_00133_00224-1              83.51390             153.66093
#>                       s_008um_00135_00235-1 s_008um_00118_00240-1
#> s_008um_00110_00228-1             207.67263             115.37078
#> s_008um_00122_00239-1             108.80056              32.98142
#> s_008um_00125_00234-1              80.39099              73.74967
#> s_008um_00124_00223-1             130.22199             144.21284
#> s_008um_00131_00230-1              51.22177             131.19760
#> s_008um_00133_00224-1              89.43819             175.43883
#>                       s_008um_00124_00225-1 s_008um_00125_00236-1
#> s_008um_00110_00228-1             114.53071             135.98865
#> s_008um_00122_00239-1             113.13073              33.93818
#> s_008um_00125_00234-1              72.43939              15.99915
#> s_008um_00124_00223-1              15.99917             104.30190
#> s_008um_00131_00230-1              68.81335              67.87639
#> s_008um_00133_00224-1              72.43563             115.36889
#>                       s_008um_00126_00247-1 s_008um_00128_00230-1
#> s_008um_00110_00228-1             198.70308             144.87177
#> s_008um_00122_00239-1              71.55017              86.52662
#> s_008um_00125_00234-1             104.30179              39.99684
#> s_008um_00124_00223-1             192.65556              64.49442
#> s_008um_00131_00230-1             141.75158              23.99756
#> s_008um_00133_00224-1             192.32112              62.47693
#>                       s_008um_00130_00238-1 s_008um_00120_00247-1
#> s_008um_00110_00228-1             178.87026             171.75764
#> s_008um_00122_00239-1              64.49137              65.96567
#> s_008um_00125_00234-1              51.22120             111.41976
#> s_008um_00124_00223-1             129.23711             194.63727
#> s_008um_00131_00230-1              64.49447             161.97534
#> s_008um_00133_00224-1             114.53590             211.34217
#>                       s_008um_00127_00232-1 s_008um_00135_00242-1
#> s_008um_00110_00228-1             139.70068              229.2059
#> s_008um_00122_00239-1              68.81322              106.7231
#> s_008um_00125_00234-1              22.62546              102.4424
#> s_008um_00124_00223-1              75.89075              175.6260
#> s_008um_00131_00230-1              35.77354              101.1876
#> s_008um_00133_00224-1              79.99372              144.8788
#>                       s_008um_00125_00227-1 s_008um_00113_00227-1
#> s_008um_00110_00228-1             120.25399              25.29562
#> s_008um_00122_00239-1              98.94861             119.99261
#> s_008um_00125_00234-1              55.99707             111.13050
#> s_008um_00124_00223-1              32.98318              93.62805
#> s_008um_00131_00230-1              53.66109             145.97206
#> s_008um_00133_00224-1              68.34511             161.77328
#>                       s_008um_00131_00245-1 s_008um_00112_00233-1
#> s_008um_00110_00228-1             216.13216              43.07904
#> s_008um_00122_00239-1              86.52641              93.28767
#> s_008um_00125_00234-1             100.23402             104.29675
#> s_008um_00124_00223-1             184.68474             124.95266
#> s_008um_00131_00230-1             119.99364             153.86712
#> s_008um_00133_00224-1             168.75093             182.76013
#>                       s_008um_00129_00232-1 s_008um_00127_00240-1
#> s_008um_00110_00228-1             155.31696             166.45639
#> s_008um_00122_00239-1              79.18910              40.78820
#> s_008um_00125_00234-1              35.77353              50.59379
#> s_008um_00124_00223-1              82.36042             138.09439
#> s_008um_00131_00230-1              22.62547              86.15697
#> s_008um_00133_00224-1              71.54923             136.69525
#>                       s_008um_00134_00248-1 s_008um_00134_00239-1
#> s_008um_00110_00228-1              249.9097             211.18778
#> s_008um_00122_00239-1              119.9909              95.99019
#> s_008um_00125_00234-1              133.1386              82.35823
#> s_008um_00124_00223-1              215.3951             150.93492
#> s_008um_00131_00230-1              145.9788              75.89070
#> s_008um_00133_00224-1              192.1566             120.26019
#>                       s_008um_00120_00229-1 s_008um_00110_00225-1
#> s_008um_00110_00228-1              80.39099              23.99875
#> s_008um_00122_00239-1              81.58014             147.50321
#> s_008um_00125_00234-1              56.56469             139.93155
#> s_008um_00124_00223-1              57.68445             113.12538
#> s_008um_00131_00230-1              88.35407             172.67985
#> s_008um_00133_00224-1             111.41582             184.15497
#>                       s_008um_00124_00237-1 s_008um_00114_00225-1
#> s_008um_00110_00228-1             133.13598              39.99627
#> s_008um_00122_00239-1              22.62545             128.98879
#> s_008um_00125_00234-1              25.29662             113.69306
#> s_008um_00124_00223-1             111.99413              81.57588
#> s_008um_00131_00230-1              79.18912             141.74719
#> s_008um_00133_00224-1             126.48139             152.19478
#>                       s_008um_00118_00237-1 s_008um_00108_00241-1
#> s_008um_00110_00228-1              96.32647              105.2176
#> s_008um_00122_00239-1              35.77404              113.1253
#> s_008um_00125_00234-1              60.92001              147.0632
#> s_008um_00124_00223-1             121.84423              192.6494
#> s_008um_00131_00230-1             118.10694              203.9403
#> s_008um_00133_00224-1             158.78123              241.8365
#>                       s_008um_00115_00230-1 s_008um_00128_00234-1
#> s_008um_00110_00228-1              43.07749             151.77543
#> s_008um_00122_00239-1              91.20834              62.47631
#> s_008um_00125_00234-1              86.15498              23.99755
#> s_008um_00124_00223-1              91.20564              93.63272
#> s_008um_00131_00230-1             127.98695              39.99684
#> s_008um_00133_00224-1             151.77381              89.43652
#>                       s_008um_00107_00227-1 s_008um_00127_00229-1
#> s_008um_00110_00228-1               25.2959             136.22137
#> s_008um_00122_00239-1              153.6636              89.43646
#> s_008um_00125_00234-1              154.4919              43.07849
#> s_008um_00124_00223-1              139.6995              53.66270
#> s_008um_00131_00230-1              193.4750              32.98173
#> s_008um_00133_00224-1              209.3584              62.47637
#>                       s_008um_00125_00223-1 s_008um_00118_00232-1
#> s_008um_00110_00228-1            126.478147              71.54811
#> s_008um_00122_00239-1            130.223080              64.49438
#> s_008um_00125_00234-1             87.995405              58.23543
#> s_008um_00124_00223-1              7.999188              86.52666
#> s_008um_00131_00230-1             73.751630             105.21268
#> s_008um_00133_00224-1             64.491712             135.98663
#>                       s_008um_00119_00223-1 s_008um_00119_00244-1
#> s_008um_00110_00228-1              82.35696             146.85212
#> s_008um_00122_00239-1             130.22394              46.64413
#> s_008um_00125_00234-1             100.23411              93.28829
#> s_008um_00124_00223-1              39.99593             172.68598
#> s_008um_00131_00230-1             111.13053             147.50048
#> s_008um_00133_00224-1             112.27412             195.28975
#>                       s_008um_00123_00239-1 s_008um_00117_00240-1
#> s_008um_00110_00228-1            136.225224             111.13319
#> s_008um_00122_00239-1              7.999181              40.78791
#> s_008um_00125_00234-1             43.078470              79.99252
#> s_008um_00124_00223-1            128.242855             147.06847
#> s_008um_00131_00230-1             96.324709             137.62424
#> s_008um_00133_00224-1            144.211088             181.00370
#>                       s_008um_00120_00225-1 s_008um_00120_00221-1
#> s_008um_00110_00228-1              83.51385              97.64324
#> s_008um_00122_00239-1             113.13131             144.87877
#> s_008um_00125_00234-1              82.36041             111.42127
#> s_008um_00124_00223-1              35.77355              35.77407
#> s_008um_00131_00230-1              96.65602             113.69309
#> s_008um_00133_00224-1             104.29653             106.72318
#>                       s_008um_00117_00228-1 s_008um_00106_00219-1
#> s_008um_00110_00228-1              55.99428              78.78667
#> s_008um_00122_00239-1              96.65912             204.88713
#> s_008um_00125_00234-1              79.99397             193.64520
#> s_008um_00124_00223-1              68.81216             147.49863
#> s_008um_00131_00230-1             113.12596             218.48502
#> s_008um_00133_00224-1             131.92579             219.65125
#>                       s_008um_00109_00219-1 s_008um_00121_00229-1
#> s_008um_00110_00228-1              72.43942              88.35405
#> s_008um_00122_00239-1             190.81858              80.39487
#> s_008um_00125_00234-1             175.44152              51.22177
#> s_008um_00124_00223-1             124.18175              53.66191
#> s_008um_00131_00230-1             196.75737              80.39100
#> s_008um_00133_00224-1             196.10361             103.98953
#>                       s_008um_00116_00223-1 s_008um_00136_00226-1
#> s_008um_00110_00228-1              62.47633             208.59301
#> s_008um_00122_00239-1             136.69688             152.82633
#> s_008um_00125_00234-1             113.69418             108.80163
#> s_008um_00124_00223-1              63.99349              98.94520
#> s_008um_00131_00230-1             132.41219              51.22034
#> s_008um_00133_00224-1             136.22142              28.84216
#>                       s_008um_00132_00229-1 s_008um_00114_00218-1
#> s_008um_00110_00228-1             176.16394              86.15701
#> s_008um_00122_00239-1             113.12730             179.76821
#> s_008um_00125_00234-1              68.81215             155.32267
#> s_008um_00124_00223-1              79.99400              89.43519
#> s_008um_00131_00230-1              11.31274             166.45649
#> s_008um_00133_00224-1              40.78982             159.38425
#>                       s_008um_00116_00236-1 s_008um_00128_00223-1
#> s_008um_00110_00228-1              79.99508             149.43694
#> s_008um_00122_00239-1              53.66107             136.69524
#> s_008um_00125_00234-1              73.74870              91.20854
#> s_008um_00124_00223-1             122.10563              31.99675
#> s_008um_00131_00230-1             129.23083              60.92295
#> s_008um_00133_00224-1             166.45357              40.78824
#>                       s_008um_00129_00231-1 s_008um_00117_00243-1
#> s_008um_00110_00228-1             153.86800             132.41632
#> s_008um_00122_00239-1              85.03409              51.22026
#> s_008um_00125_00234-1              39.99628              96.32465
#> s_008um_00124_00223-1              75.46748             169.50613
#> s_008um_00131_00230-1              17.88677             152.82625
#> s_008um_00133_00224-1              64.49342             198.69955
#>                       s_008um_00113_00230-1 s_008um_00110_00224-1
#> s_008um_00110_00228-1              28.84215              31.99833
#> s_008um_00122_00239-1             101.81643             153.66532
#> s_008um_00125_00234-1             101.18361             144.21078
#> s_008um_00124_00223-1             104.29723             112.27380
#> s_008um_00131_00230-1             143.98532             174.70635
#> s_008um_00133_00224-1             167.02775             183.98129
#>                       s_008um_00125_00219-1 s_008um_00116_00228-1
#> s_008um_00110_00228-1             139.92931              47.99510
#> s_008um_00122_00239-1             161.78092             100.23407
#> s_008um_00125_00234-1             119.99376              86.52646
#> s_008um_00124_00223-1              32.98291              75.46460
#> s_008um_00131_00230-1             100.23414             121.05003
#> s_008um_00133_00224-1              75.46587             139.69958
#>                       s_008um_00112_00230-1 s_008um_00114_00230-1
#> s_008um_00110_00228-1              22.62588              35.77406
#> s_008um_00122_00239-1             107.62136              96.32645
#> s_008um_00125_00234-1             108.80168              93.62914
#> s_008um_00124_00223-1             111.12873              97.64325
#> s_008um_00131_00230-1             151.98450             135.98614
#> s_008um_00133_00224-1             174.70466             159.38253
#>                       s_008um_00123_00244-1 s_008um_00106_00226-1
#> s_008um_00110_00228-1             164.91375              35.77406
#> s_008um_00122_00239-1              40.79004             164.91212
#> s_008um_00125_00234-1              81.57953             164.90971
#> s_008um_00124_00223-1             168.18134             145.97118
#> s_008um_00131_00230-1             128.98671             202.52401
#> s_008um_00133_00224-1             178.87295             216.56950
#>                       s_008um_00116_00233-1 s_008um_00109_00241-1
#> s_008um_00110_00228-1              62.47746              104.3015
#> s_008um_00122_00239-1              67.87761              105.2126
#> s_008um_00125_00234-1              72.43587              139.6998
#> s_008um_00124_00223-1             102.44173              187.4306
#> s_008um_00131_00230-1             122.36379              196.7543
#> s_008um_00133_00224-1             153.86792              235.2649
#>                       s_008um_00106_00228-1 s_008um_00136_00231-1
#> s_008um_00110_00228-1              31.99673             209.35928
#> s_008um_00122_00239-1             155.31984             128.98353
#> s_008um_00125_00234-1             159.38415              91.20464
#> s_008um_00124_00223-1             149.43691             115.36864
#> s_008um_00131_00230-1             200.61887              40.78823
#> s_008um_00133_00224-1             218.33492              60.92294
#>                       s_008um_00129_00229-1 s_008um_00122_00231-1
#> s_008um_00110_00228-1             152.19503              98.94515
#> s_008um_00122_00239-1              97.64487              63.99662
#> s_008um_00125_00234-1              51.22086              33.93881
#> s_008um_00124_00223-1              62.47804              65.96578
#> s_008um_00131_00230-1              17.88703              72.43560
#> s_008um_00133_00224-1              51.22090             104.29727
#>                       s_008um_00131_00229-1 s_008um_00116_00222-1
#> s_008um_00110_00228-1            168.173392              67.87639
#> s_008um_00122_00239-1            107.619969             144.21453
#> s_008um_00125_00234-1             62.476342             119.99265
#> s_008um_00124_00223-1             73.751072              64.49170
#> s_008um_00131_00230-1              7.999582             135.98869
#> s_008um_00133_00224-1             43.078522             136.92442
#>                       s_008um_00130_00246-1 s_008um_00125_00233-1
#> s_008um_00110_00228-1             215.24269            126.479524
#> s_008um_00122_00239-1              85.03504             53.661866
#> s_008um_00125_00234-1             103.99438              7.999579
#> s_008um_00124_00223-1             190.14805             80.394916
#> s_008um_00131_00230-1             128.24279             53.660307
#> s_008um_00133_00224-1             177.61887             96.324765
#>                       s_008um_00113_00235-1 s_008um_00106_00224-1
#> s_008um_00110_00228-1              60.92292              45.25177
#> s_008um_00122_00239-1              78.78398             175.44147
#> s_008um_00125_00234-1              96.32279             171.75292
#> s_008um_00124_00223-1             130.21959             144.20723
#> s_008um_00131_00230-1             149.43690             205.65982
#> s_008um_00133_00224-1             182.58548             215.97802
#>                       s_008um_00136_00228-1 s_008um_00124_00233-1
#> s_008um_00110_00228-1             207.97882             118.91777
#> s_008um_00122_00239-1             142.42286              50.59323
#> s_008um_00125_00234-1             100.22989              11.31294
#> s_008um_00124_00223-1             103.99087              79.99583
#> s_008um_00131_00230-1              43.07697              60.92005
#> s_008um_00133_00224-1              39.99755             101.81463
#>                       s_008um_00130_00230-1 s_008um_00134_00242-1
#> s_008um_00110_00228-1            160.781988             222.26096
#> s_008um_00122_00239-1             96.324705              98.94513
#> s_008um_00125_00234-1             51.220309              96.32588
#> s_008um_00124_00223-1             73.751630             171.75770
#> s_008um_00131_00230-1              7.999187              98.94944
#> s_008um_00133_00224-1             53.661926             144.21460
#>                       s_008um_00126_00226-1 s_008um_00107_00229-1
#> s_008um_00110_00228-1             128.98278              25.29562
#> s_008um_00122_00239-1             108.80501             144.21073
#> s_008um_00125_00234-1              64.49449             149.43831
#> s_008um_00124_00223-1              28.84272             144.20730
#> s_008um_00131_00230-1              51.22123             192.14715
#> s_008um_00133_00224-1              58.23491             211.78932
#>                       s_008um_00131_00228-1 s_008um_00116_00232-1
#> s_008um_00110_00228-1             167.98288              57.68431
#> s_008um_00122_00239-1             113.69211              73.75159
#> s_008um_00125_00234-1              67.87640              73.74928
#> s_008um_00124_00223-1              68.81336              96.32473
#> s_008um_00131_00230-1              15.99917             121.04944
#> s_008um_00133_00224-1              35.77462             150.29135
#>                       s_008um_00123_00230-1 s_008um_00136_00229-1
#> s_008um_00110_00228-1             105.21325             208.13275
#> s_008um_00122_00239-1              72.43906             137.62429
#> s_008um_00125_00234-1              35.77512              96.65469
#> s_008um_00124_00223-1              56.56540             107.32220
#> s_008um_00131_00230-1              63.99349              40.78795
#> s_008um_00133_00224-1              93.28623              46.64495
#>                       s_008um_00131_00231-1 s_008um_00106_00221-1
#> s_008um_00110_00228-1            169.688929              64.49443
#> s_008um_00122_00239-1             96.324147             192.65296
#> s_008um_00125_00234-1             53.660304             184.15956
#> s_008um_00124_00223-1             85.035674             144.87180
#> s_008um_00131_00230-1              7.999582             212.54610
#> s_008um_00133_00224-1             58.237357             217.30772
#>                       s_008um_00126_00222-1 s_008um_00132_00248-1
#> s_008um_00110_00228-1             136.69015              237.8402
#> s_008um_00122_00239-1             139.70574              107.6213
#> s_008um_00125_00234-1              96.32755              125.2128
#> s_008um_00124_00223-1              17.88678              209.9795
#> s_008um_00131_00230-1              75.46749              144.2145
#> s_008um_00133_00224-1              58.23547              192.1563
#>                       s_008um_00136_00238-1 s_008um_00118_00229-1
#> s_008um_00110_00228-1             222.83426              64.49167
#> s_008um_00122_00239-1             112.27377              86.15805
#> s_008um_00125_00234-1              93.62913              68.81333
#> s_008um_00124_00223-1             153.66533              67.87641
#> s_008um_00131_00230-1              75.46744             104.29679
#> s_008um_00133_00224-1             114.53675             126.47818
#>                       s_008um_00130_00221-1 s_008um_00125_00226-1
#> s_008um_00110_00228-1             169.49966             121.04944
#> s_008um_00122_00239-1             157.57113             106.72700
#> s_008um_00125_00234-1             111.41992              63.99665
#> s_008um_00124_00223-1              50.59129              25.29692
#> s_008um_00131_00230-1              72.43942              57.68432
#> s_008um_00133_00224-1              33.93883              65.96291
#>                       s_008um_00128_00233-1 s_008um_00131_00233-1
#> s_008um_00110_00228-1             149.43832             172.67982
#> s_008um_00122_00239-1              67.87637              86.52498
#> s_008um_00125_00234-1              25.29563              48.65706
#> s_008um_00124_00223-1              86.15809              97.64659
#> s_008um_00131_00230-1              33.93820              23.99874
#> s_008um_00133_00224-1              82.35916              73.75206
#>                       s_008um_00115_00227-1 s_008um_00121_00223-1
#> s_008um_00110_00228-1              40.78792              96.65466
#> s_008um_00122_00239-1             111.13319             128.24314
#> s_008um_00125_00234-1              97.64492              93.63272
#> s_008um_00124_00223-1              78.78295              23.99756
#> s_008um_00131_00230-1             130.21795              97.64494
#> s_008um_00133_00224-1             145.97122              96.32316
#>                       s_008um_00132_00246-1 s_008um_00121_00239-1
#> s_008um_00110_00228-1             227.38602            124.442306
#> s_008um_00122_00239-1              97.64486              7.999181
#> s_008um_00125_00234-1             111.13313             51.220834
#> s_008um_00124_00223-1             194.80252            130.223077
#> s_008um_00131_00230-1             128.24308            107.619406
#> s_008um_00133_00224-1             176.17228            153.662594
#>                       s_008um_00112_00228-1 s_008um_00130_00218-1
#> s_008um_00110_00228-1              15.99836             178.86772
#> s_008um_00122_00239-1             118.92071             179.76604
#> s_008um_00125_00234-1             114.53268             134.09619
#> s_008um_00124_00223-1             103.98949              62.47639
#> s_008um_00131_00230-1             152.82458              96.32789
#> s_008um_00133_00224-1             171.00279              53.66272
#>                       s_008um_00126_00244-1 s_008um_00137_00246-1
#> s_008um_00110_00228-1             181.00696              259.5793
#> s_008um_00122_00239-1              51.22174              132.4121
#> s_008um_00125_00234-1              80.39484              135.7552
#> s_008um_00124_00223-1             168.75151              211.3455
#> s_008um_00131_00230-1             118.92091              136.6968
#> s_008um_00133_00224-1             169.50617              178.8763
#>                       s_008um_00115_00236-1 s_008um_00119_00220-1
#> s_008um_00110_00228-1              75.46746              96.32417
#> s_008um_00122_00239-1              60.92082             153.87526
#> s_008um_00125_00234-1              81.57583             121.84589
#> s_008um_00124_00223-1             126.48135              46.64387
#> s_008um_00131_00230-1             136.69011             124.95496
#> s_008um_00133_00224-1             173.05000             116.47094
#>                       s_008um_00128_00224-1 s_008um_00116_00227-1
#> s_008um_00110_00228-1             147.49746              48.65705
#> s_008um_00122_00239-1             129.23547             107.32534
#> s_008um_00125_00234-1              83.51733              91.20725
#> s_008um_00124_00223-1              32.98173              71.54708
#> s_008um_00131_00230-1              53.66269             122.36467
#> s_008um_00133_00224-1              39.99594             138.08715
#>                       s_008um_00126_00232-1 s_008um_00135_00232-1
#> s_008um_00110_00228-1             131.92687             202.52401
#> s_008um_00122_00239-1              64.49336             118.10695
#> s_008um_00125_00234-1              17.88730              81.57587
#> s_008um_00124_00223-1              73.75262             113.69307
#> s_008um_00131_00230-1              43.07696              35.77406
#> s_008um_00133_00224-1              85.03415              65.96634
#>                       s_008um_00126_00243-1 s_008um_00124_00246-1
#> s_008um_00110_00228-1             175.44143             182.41664
#> s_008um_00122_00239-1              45.25173              58.23783
#> s_008um_00125_00234-1              72.43933              96.32744
#> s_008um_00124_00223-1             160.78976             183.99029
#> s_008um_00131_00230-1             111.41983             139.70454
#> s_008um_00133_00224-1             161.97723             190.14524
#>                       s_008um_00125_00237-1 s_008um_00128_00220-1
#> s_008um_00110_00228-1             139.93153             157.56591
#> s_008um_00122_00239-1              28.84165             159.38898
#> s_008um_00125_00234-1              23.99873             114.53593
#> s_008um_00124_00223-1             112.27959              39.99631
#> s_008um_00131_00230-1              73.75027              83.51819
#> s_008um_00133_00224-1             122.10567              51.22125
#>                       s_008um_00109_00227-1 s_008um_00110_00230-1
#> s_008um_00110_00228-1              11.31294              15.99916
#> s_008um_00122_00239-1             141.52452             119.99093
#> s_008um_00125_00234-1             139.70179             124.18169
#> s_008um_00124_00223-1             124.18058             125.20736
#> s_008um_00131_00230-1             177.61132             167.98287
#> s_008um_00133_00224-1             193.47421             190.13822
#>                       s_008um_00111_00225-1 s_008um_00118_00246-1
#> s_008um_00110_00228-1              25.29663             157.57316
#> s_008um_00122_00239-1             142.42705              64.49331
#> s_008um_00125_00234-1             133.13601             111.13134
#> s_008um_00124_00223-1             105.21269             190.14632
#> s_008um_00131_00230-1             164.90862             164.91076
#> s_008um_00133_00224-1             176.16368             213.00004
#>                       s_008um_00124_00243-1 s_008um_00113_00226-1
#> s_008um_00110_00228-1             164.13534              28.84166
#> s_008um_00122_00239-1              35.77509             126.48351
#> s_008um_00125_00234-1              72.43904             115.36861
#> s_008um_00124_00223-1             159.99158              91.20464
#> s_008um_00131_00230-1             118.11013             147.49860
#> s_008um_00133_00224-1             168.17882             160.78145
#>                       s_008um_00125_00238-1 s_008um_00133_00236-1
#> s_008um_00110_00228-1             144.21074             194.79500
#> s_008um_00122_00239-1              25.29562              91.20461
#> s_008um_00125_00234-1              31.99831              65.96344
#> s_008um_00124_00223-1             120.26019             126.48354
#> s_008um_00131_00230-1              79.99367              50.59381
#> s_008um_00133_00224-1             128.98679              95.99499
#>                       s_008um_00120_00227-1 s_008um_00114_00228-1
#> s_008um_00110_00228-1              80.39069              31.99673
#> s_008um_00122_00239-1              97.31923             108.80512
#> s_008um_00125_00234-1              68.81444             100.23140
#> s_008um_00124_00223-1              45.25094              89.43384
#> s_008um_00131_00230-1              91.20549             136.92437
#> s_008um_00133_00224-1             106.72231             155.31586
#>                       s_008um_00124_00229-1 s_008um_00127_00228-1
#> s_008um_00110_00228-1             112.27407             135.98613
#> s_008um_00122_00239-1              81.57956              96.65779
#> s_008um_00125_00234-1              40.79008              50.59326
#> s_008um_00124_00223-1              47.99750              46.64495
#> s_008um_00131_00230-1              56.56299              35.77406
#> s_008um_00133_00224-1              82.35701              57.68337
#>                       s_008um_00124_00226-1 s_008um_00121_00230-1
#> s_008um_00110_00228-1             113.12537              89.43402
#> s_008um_00122_00239-1             105.21762              72.43936
#> s_008um_00125_00234-1              64.49478              45.25175
#> s_008um_00124_00223-1              23.99876              60.92214
#> s_008um_00131_00230-1              64.49279              79.99185
#> s_008um_00133_00224-1              73.74876             107.32064
#>                       s_008um_00126_00246-1 s_008um_00121_00232-1
#> s_008um_00110_00228-1             192.65287              93.62914
#> s_008um_00122_00239-1              64.49434              56.56564
#> s_008um_00125_00234-1              96.32774              35.77405
#> s_008um_00124_00223-1             184.68482              75.88991
#> s_008um_00131_00230-1             134.09604              81.57587
#> s_008um_00133_00224-1             184.68280             115.36670
#>                       s_008um_00134_00228-1 s_008um_00135_00243-1
#> s_008um_00110_00228-1             191.98044              233.2192
#> s_008um_00122_00239-1             130.21904              108.8017
#> s_008um_00125_00234-1              86.52502              107.6213
#> s_008um_00124_00223-1              89.43517              182.5931
#> s_008um_00131_00230-1              28.84168              108.8061
#> s_008um_00133_00224-1              32.98318              152.8320
#>                       s_008um_00127_00227-1 s_008um_00119_00246-1
#> s_008um_00110_00228-1             136.22108             160.98796
#> s_008um_00122_00239-1             103.99309              60.92204
#> s_008um_00125_00234-1              58.23733             107.32369
#> s_008um_00124_00223-1              39.99756             188.28655
#> s_008um_00131_00230-1              39.99699             159.98726
#> s_008um_00133_00224-1              53.66033             208.59877
#>                       s_008um_00127_00224-1 s_008um_00113_00224-1
#> s_008um_00110_00228-1             139.69955              39.99683
#> s_008um_00122_00239-1             126.48315             139.93480
#> s_008um_00125_00234-1              81.57961             124.95493
#> s_008um_00124_00223-1              25.29592              88.35379
#> s_008um_00131_00230-1              57.68542             151.77546
#> s_008um_00133_00224-1              47.99513             159.98374
#>                       s_008um_00127_00247-1 s_008um_00111_00231-1
#> s_008um_00110_00228-1             203.94736              25.29691
#> s_008um_00122_00239-1              75.46739             108.80346
#> s_008um_00125_00234-1             105.21813             114.53155
#> s_008um_00124_00223-1             193.48425             122.10291
#> s_008um_00131_00230-1             139.70565             160.18341
#> s_008um_00133_00224-1             190.14635             184.67540
#>                       s_008um_00123_00241-1 s_008um_00131_00248-1
#> s_008um_00110_00228-1             147.06817              231.9838
#> s_008um_00122_00239-1              17.88755              101.8164
#> s_008um_00125_00234-1              58.23729              121.8458
#> s_008um_00124_00223-1             144.21430              207.6813
#> s_008um_00131_00230-1             108.80322              143.9924
#> s_008um_00133_00224-1             157.77312              192.6550
#>                       s_008um_00131_00234-1 s_008um_00120_00246-1
#> s_008um_00110_00228-1             174.70631             164.72072
#> s_008um_00122_00239-1              82.35695              58.23726
#> s_008um_00125_00234-1              47.99511             103.99301
#> s_008um_00124_00223-1             104.30116             186.75116
#> s_008um_00131_00230-1              31.99832             155.31988
#> s_008um_00133_00224-1              81.57962             204.41588
#>                       s_008um_00134_00243-1 s_008um_00106_00237-1
#> s_008um_00110_00228-1              226.3974              78.78549
#> s_008um_00122_00239-1              101.1836             128.98329
#> s_008um_00125_00234-1              101.8164             153.86705
#> s_008um_00124_00223-1              178.8756             182.41119
#> s_008um_00131_00230-1              106.7278             207.67059
#> s_008um_00133_00224-1              152.2025             239.70922
#>                       s_008um_00130_00223-1 s_008um_00115_00221-1
#> s_008um_00110_00228-1             164.90720              68.81325
#> s_008um_00122_00239-1             143.09839             154.49752
#> s_008um_00125_00234-1              96.65785             131.20165
#> s_008um_00124_00223-1              47.99513              73.74932
#> s_008um_00131_00230-1              56.56569             146.84844
#> s_008um_00133_00224-1              25.29592             145.97211
#>                       s_008um_00112_00227-1 s_008um_00135_00219-1
#> s_008um_00110_00228-1              17.88676             212.54366
#> s_008um_00122_00239-1             124.95601             190.81542
#> s_008um_00125_00234-1             118.10876             144.21116
#> s_008um_00124_00223-1             101.18252              93.62812
#> s_008um_00131_00230-1             153.86801              93.63168
#> s_008um_00133_00224-1             169.68810              43.07854
#>                       s_008um_00124_00240-1 s_008um_00129_00219-1
#> s_008um_00110_00228-1             147.50207             168.17360
#> s_008um_00122_00239-1              17.88702             169.50622
#> s_008um_00125_00234-1              48.65931             124.18597
#> s_008um_00124_00223-1             135.99286              51.22035
#> s_008um_00131_00230-1              97.64487              89.43823
#> s_008um_00133_00224-1             146.84989              51.22181
#>                       s_008um_00126_00245-1 s_008um_00137_00224-1
#> s_008um_00110_00228-1             186.74938             218.33495
#> s_008um_00122_00239-1              57.68536             169.69101
#> s_008um_00125_00234-1              88.35829             124.95273
#> s_008um_00124_00223-1             176.71668             104.29684
#> s_008um_00131_00230-1             126.48309              67.87644
#> s_008um_00133_00224-1             177.07638              31.99676
#>                       s_008um_00127_00225-1 s_008um_00130_00222-1
#> s_008um_00110_00228-1             138.08711             167.02774
#> s_008um_00122_00239-1             118.92095             150.29608
#> s_008um_00125_00234-1              73.75204             103.99315
#> s_008um_00124_00223-1              28.84216              48.65709
#> s_008um_00131_00230-1              51.22179              64.49481
#> s_008um_00133_00224-1              48.65709              28.84217
#>                       s_008um_00126_00239-1 s_008um_00114_00229-1
#> s_008um_00110_00228-1             155.31984              32.98172
#> s_008um_00122_00239-1              31.99673             102.44353
#> s_008um_00125_00234-1              40.79006              96.65599
#> s_008um_00124_00223-1             128.98955              93.28620
#> s_008um_00131_00230-1              82.35911             136.22138
#> s_008um_00133_00224-1             132.41453             157.15887
#>                       s_008um_00123_00219-1 s_008um_00122_00230-1
#> s_008um_00110_00228-1             126.47918              97.31469
#> s_008um_00122_00239-1             160.19133              71.99620
#> s_008um_00125_00234-1             121.05585              39.99754
#> s_008um_00124_00223-1              32.98319              58.23735
#> s_008um_00131_00230-1             108.80519              71.99267
#> s_008um_00133_00224-1              89.43519             100.22990
#>                       s_008um_00118_00247-1 s_008um_00121_00226-1
#> s_008um_00110_00228-1              164.9153              89.43344
#> s_008um_00122_00239-1               71.5491             104.30186
#> s_008um_00125_00234-1              118.1101              71.55024
#> s_008um_00124_00223-1              197.8972              33.93821
#> s_008um_00131_00230-1              171.1938              86.15500
#> s_008um_00133_00224-1              219.6558              97.31416
#>                       s_008um_00131_00219-1 s_008um_00107_00228-1
#> s_008um_00110_00228-1             182.76017              23.99755
#> s_008um_00122_00239-1             175.44188             148.79728
#> s_008um_00125_00234-1             129.23555             151.77542
#> s_008um_00124_00223-1              64.49182             141.74576
#> s_008um_00131_00230-1              87.99545             192.64622
#> s_008um_00133_00224-1              43.07907             210.42537
#>                       s_008um_00111_00229-1 s_008um_00128_00225-1
#> s_008um_00110_00228-1              11.31294             145.97119
#> s_008um_00122_00239-1             118.92015             121.84423
#> s_008um_00125_00234-1             118.91777              75.88991
#> s_008um_00124_00223-1             114.53109              35.77407
#> s_008um_00131_00230-1             160.18371              46.64495
#> s_008um_00133_00224-1             180.46958              40.78796
#>                       s_008um_00126_00240-1 s_008um_00127_00223-1
#> s_008um_00110_00228-1             159.98792             141.74578
#> s_008um_00122_00239-1              32.98171             134.09611
#> s_008um_00125_00234-1              48.65960              89.43762
#> s_008um_00124_00223-1             136.93095              23.99756
#> s_008um_00131_00230-1              89.43647              64.49442
#> s_008um_00133_00224-1             139.70463              48.65737
#>                       s_008um_00122_00218-1 s_008um_00125_00232-1
#> s_008um_00110_00228-1             124.95269             124.18170
#> s_008um_00122_00239-1             167.99122              60.92209
#> s_008um_00125_00234-1             130.22400              15.99916
#> s_008um_00124_00223-1              43.07907              72.43941
#> s_008um_00131_00230-1             119.99268              50.59127
#> s_008um_00133_00224-1             100.23146              90.50189
#>                       s_008um_00118_00225-1 s_008um_00119_00232-1
#> s_008um_00110_00228-1              68.34506              78.78401
#> s_008um_00122_00239-1             116.47576              60.92290
#> s_008um_00125_00234-1              91.20837              50.59181
#> s_008um_00124_00223-1              50.59127              82.35914
#> s_008um_00131_00230-1             111.41716              97.31412
#> s_008um_00133_00224-1             120.25404             128.98357
#>                       s_008um_00115_00229-1 s_008um_00132_00219-1
#> s_008um_00110_00228-1              40.78821             190.13863
#> s_008um_00122_00239-1              97.64655             178.87303
#> s_008um_00125_00234-1              89.43514             132.41459
#> s_008um_00124_00223-1              86.52501              71.54712
#> s_008um_00131_00230-1             128.23686              88.35814
#> s_008um_00133_00224-1             149.43696              40.79012
#>                       s_008um_00107_00225-1 s_008um_00120_00233-1
#> s_008um_00110_00228-1              33.93883              89.43514
#> s_008um_00122_00239-1             164.13481              50.59379
#> s_008um_00125_00234-1             160.98326              40.78821
#> s_008um_00124_00223-1             136.92379              86.15700
#> s_008um_00131_00230-1             196.10355              91.20463
#> s_008um_00133_00224-1             208.13248             126.47919
#>                       s_008um_00122_00224-1 s_008um_00132_00247-1
#> s_008um_00110_00228-1             101.18251              232.5343
#> s_008um_00122_00239-1             119.99369              102.4424
#> s_008um_00125_00234-1              83.51816              118.1119
#> s_008um_00124_00223-1              17.88677              202.3752
#> s_008um_00131_00230-1              86.52648              136.2280
#> s_008um_00133_00224-1              87.99107              184.1640
#>                       s_008um_00119_00248-1 s_008um_00119_00229-1
#> s_008um_00110_00228-1             175.44413              72.43588
#> s_008um_00122_00239-1              75.88979              83.51813
#> s_008um_00125_00234-1             121.84411              62.47746
#> s_008um_00124_00223-1             203.94887              62.47691
#> s_008um_00131_00230-1             173.05317              96.32313
#> s_008um_00133_00224-1             222.26280             118.91644
#>                       s_008um_00122_00232-1 s_008um_00133_00231-1
#> s_008um_00110_00228-1             101.18362             185.54029
#> s_008um_00122_00239-1              55.99704             108.80157
#> s_008um_00125_00234-1              28.84215              68.34508
#> s_008um_00124_00223-1              73.75205              96.32594
#> s_008um_00131_00230-1              73.74873              17.88703
#> s_008um_00133_00224-1             108.80163              55.99709
#>                       s_008um_00131_00237-1 s_008um_00119_00241-1
#> s_008um_00110_00228-1             182.76252             126.48350
#> s_008um_00122_00239-1              73.74870              28.84164
#> s_008um_00125_00234-1              53.66107              73.75023
#> s_008um_00124_00223-1             125.21292             149.44323
#> s_008um_00131_00230-1              55.99705             130.21901
#> s_008um_00133_00224-1             105.21767             176.16737
#>                       s_008um_00127_00221-1 s_008um_00118_00238-1
#> s_008um_00110_00228-1             147.06335             102.44354
#> s_008um_00122_00239-1             149.44327              32.98171
#> s_008um_00125_00234-1             105.21768              64.49174
#> s_008um_00124_00223-1              28.84169             129.23547
#> s_008um_00131_00230-1              78.78666             122.10289
#> s_008um_00133_00224-1              53.66111             164.13184
#>                       s_008um_00124_00227-1 s_008um_00130_00219-1
#> s_008um_00110_00228-1             112.27378             175.43612
#> s_008um_00122_00239-1              97.31865             172.31401
#> s_008um_00125_00234-1              56.56567             126.48322
#> s_008um_00124_00223-1              31.99834              57.68338
#> s_008um_00131_00230-1              60.92086              88.35842
#> s_008um_00133_00224-1              75.88692              46.64497
#>                       s_008um_00128_00218-1 s_008um_00132_00230-1
#> s_008um_00110_00228-1             164.71398            176.708128
#> s_008um_00122_00239-1             174.71202            107.619411
#> s_008um_00125_00234-1             130.22315             64.491774
#> s_008um_00124_00223-1              51.22091             85.035117
#> s_008um_00131_00230-1              98.94955              7.999187
#> s_008um_00133_00224-1              62.47806             48.659366
#>                       s_008um_00109_00230-1 s_008um_00109_00226-1
#> s_008um_00110_00228-1              17.88729              17.88756
#> s_008um_00122_00239-1             126.48130             147.06819
#> s_008um_00125_00234-1             131.92686             143.09623
#> s_008um_00124_00223-1             132.41030             122.36380
#> s_008um_00131_00230-1             175.98205             178.86807
#> s_008um_00133_00224-1             197.88864             192.64568
#>                       s_008um_00117_00230-1 s_008um_00113_00232-1
#> s_008um_00110_00228-1              58.23544              39.99754
#> s_008um_00122_00239-1              82.36038              91.20722
#> s_008um_00125_00234-1              71.54811              97.31468
#> s_008um_00124_00223-1              79.18914             113.69101
#> s_008um_00131_00230-1             111.98859             144.87118
#> s_008um_00133_00224-1             136.69017             172.30782
#>                       s_008um_00113_00222-1 s_008um_00130_00244-1
#> s_008um_00110_00228-1              53.66190             204.88481
#> s_008um_00122_00239-1             153.87450              75.46578
#> s_008um_00125_00234-1             135.75529              89.43774
#> s_008um_00124_00223-1              88.35408             174.71363
#> s_008um_00131_00230-1             157.56805             112.27923
#> s_008um_00133_00224-1             160.78204             161.78087
#>                       s_008um_00113_00233-1 s_008um_00137_00232-1
#> s_008um_00110_00228-1              46.64494             218.33607
#> s_008um_00122_00239-1              86.52643             132.41030
#> s_008um_00125_00234-1              96.32309              97.31414
#> s_008um_00124_00223-1             118.91800             126.48135
#> s_008um_00131_00230-1             145.97117              50.59182
#> s_008um_00133_00224-1             175.43609              71.55025
#>                       s_008um_00136_00240-1 s_008um_00137_00237-1
#> s_008um_00110_00228-1             229.06534             227.66314
#> s_008um_00122_00239-1             112.27405             121.04942
#> s_008um_00125_00234-1             100.23138              98.94515
#> s_008um_00124_00223-1             166.45917             152.82967
#> s_008um_00131_00230-1              89.43777              73.75159
#> s_008um_00133_00224-1             130.22394             108.80616
#>                       s_008um_00110_00229-1 s_008um_00108_00229-1
#> s_008um_00110_00228-1               7.99958              17.88676
#> s_008um_00122_00239-1             124.95489             137.62664
#> s_008um_00125_00234-1             126.47952             141.74715
#> s_008um_00124_00223-1             121.84007             136.69013
#> s_008um_00131_00230-1             168.17338             184.15521
#> s_008um_00133_00224-1             188.27817             203.93968
#>                       s_008um_00123_00222-1 s_008um_00122_00226-1
#> s_008um_00110_00228-1             114.53109              97.31411
#> s_008um_00122_00239-1             136.22778             103.99453
#> s_008um_00125_00234-1              97.31928              68.34844
#> s_008um_00124_00223-1              11.31294              28.84223
#> s_008um_00131_00230-1              90.50354              78.78402
#> s_008um_00133_00224-1              81.57648              89.43349
#>                       s_008um_00129_00240-1 s_008um_00120_00226-1
#> s_008um_00110_00228-1             179.76330              81.57585
#> s_008um_00122_00239-1              56.56296             105.21820
#> s_008um_00125_00234-1              57.68538              75.46747
#> s_008um_00124_00223-1             141.75306              39.99630
#> s_008um_00131_00230-1              81.57957              93.62916
#> s_008um_00133_00224-1             131.93152             105.21272
#>                       s_008um_00124_00224-1 s_008um_00118_00226-1
#> s_008um_00110_00228-1            116.469754              65.96286
#> s_008um_00122_00239-1            121.055212             108.80613
#> s_008um_00125_00234-1             80.394908              85.03566
#> s_008um_00124_00223-1              7.999586              53.66031
#> s_008um_00131_00230-1             73.751068             108.80171
#> s_008um_00133_00224-1             71.992695             121.04948
#>                       s_008um_00109_00225-1 s_008um_00116_00235-1
#> s_008um_00110_00228-1              25.29692              73.75161
#> s_008um_00122_00239-1             152.82965              57.68429
#> s_008um_00125_00234-1             146.84841              72.43557
#> s_008um_00124_00223-1             121.04945             115.36886
#> s_008um_00131_00230-1             180.47100             126.47813
#> s_008um_00133_00224-1             192.14692             161.97217
#>                       s_008um_00135_00244-1 s_008um_00123_00238-1
#> s_008um_00110_00228-1              237.4343             131.19994
#> s_008um_00122_00239-1              111.4171              11.31272
#> s_008um_00125_00234-1              113.1293              35.77458
#> s_008um_00124_00223-1              189.6417             120.25989
#> s_008um_00131_00230-1              116.4757              90.50184
#> s_008um_00133_00224-1              160.7898             137.62651
#>                       s_008um_00136_00220-1 s_008um_00111_00226-1
#> s_008um_00110_00228-1             217.60123              17.88729
#> s_008um_00122_00239-1             188.79200             136.22635
#> s_008um_00125_00234-1             142.42461             128.98556
#> s_008um_00124_00223-1              98.94438             106.72228
#> s_008um_00131_00230-1              89.43657             163.15289
#> s_008um_00133_00224-1              39.99689             176.70758
#>                       s_008um_00135_00245-1 s_008um_00113_00229-1
#> s_008um_00110_00228-1              241.8406               25.2959
#> s_008um_00122_00239-1              114.5326              107.6219
#> s_008um_00125_00234-1              118.9207              103.9908
#> s_008um_00124_00223-1              196.7631              100.2299
#> s_008um_00131_00230-1              124.1870              144.2075
#> s_008um_00133_00224-1              168.7515              164.9072
#>                       s_008um_00106_00227-1 s_008um_00126_00218-1
#> s_008um_00110_00228-1              32.98172             150.92921
#> s_008um_00122_00239-1             159.98792             171.01066
#> s_008um_00125_00234-1             161.97305             128.24292
#> s_008um_00124_00223-1             147.49744              43.07854
#> s_008um_00131_00230-1             201.41489             103.99452
#> s_008um_00133_00224-1             217.30681              73.75109
#>                       s_008um_00111_00228-1 s_008um_00133_00233-1
#> s_008um_00110_00228-1              7.999182             188.27957
#> s_008um_00122_00239-1            124.442306             100.22984
#> s_008um_00125_00234-1            121.841684              64.49139
#> s_008um_00124_00223-1            111.415778             107.62196
#> s_008um_00131_00230-1            160.781992              28.84270
#> s_008um_00133_00224-1            178.866943              71.99625
#>                       s_008um_00134_00244-1 s_008um_00130_00243-1
#> s_008um_00110_00228-1              230.7372             199.98488
#> s_008um_00122_00239-1              103.9908              71.54808
#> s_008um_00125_00234-1              107.6219              82.36035
#> s_008um_00124_00223-1              186.0651             167.03627
#> s_008um_00131_00230-1              114.5367             104.30155
#> s_008um_00133_00224-1              160.1916             153.87437
#>                       s_008um_00135_00239-1 s_008um_00122_00240-1
#> s_008um_00110_00228-1             218.48493            135.755239
#> s_008um_00122_00239-1             103.98937              7.999574
#> s_008um_00125_00234-1              89.43512             53.661862
#> s_008um_00124_00223-1             155.32261            136.930365
#> s_008um_00131_00230-1              78.78660            107.619961
#> s_008um_00133_00224-1             121.05581            155.319969
#>                       s_008um_00117_00236-1 s_008um_00122_00220-1
#> s_008um_00110_00228-1              85.03565             115.36667
#> s_008um_00122_00239-1              46.64383             151.99204
#> s_008um_00125_00234-1              65.96285             114.53678
#> s_008um_00124_00223-1             118.11017              28.84272
#> s_008um_00131_00230-1             121.84006             107.62198
#> s_008um_00133_00224-1             159.98515              93.62919
#>                       s_008um_00115_00228-1 s_008um_00135_00240-1
#> s_008um_00110_00228-1              39.99591             221.82778
#> s_008um_00122_00239-1             104.30113             104.29675
#> s_008um_00125_00234-1              93.28769              93.28767
#> s_008um_00124_00223-1              82.35698             161.97814
#> s_008um_00131_00230-1             128.98337              86.15804
#> s_008um_00133_00224-1             147.49749             128.98955
#>                       s_008um_00126_00235-1 s_008um_00117_00235-1
#> s_008um_00110_00228-1             139.70179              79.19057
#> s_008um_00122_00239-1              45.25090              51.22120
#> s_008um_00125_00234-1              11.31294              64.49137
#> s_008um_00124_00223-1              97.31927             111.13144
#> s_008um_00131_00230-1              56.56366             118.91639
#> s_008um_00133_00224-1             104.29945             155.31723
#>                       s_008um_00133_00229-1 s_008um_00130_00235-1
#> s_008um_00110_00228-1             184.15523             169.50155
#> s_008um_00122_00239-1             118.91800              71.54705
#> s_008um_00125_00234-1              75.46460              40.78822
#> s_008um_00124_00223-1              86.52648             107.32537
#> s_008um_00131_00230-1              17.88677              40.78980
#> s_008um_00133_00224-1              39.99792              91.20854
#>                       s_008um_00109_00224-1 s_008um_00128_00242-1
#> s_008um_00110_00228-1              32.98317             182.41445
#> s_008um_00122_00239-1             158.78520              53.66106
#> s_008um_00125_00234-1             150.93166              68.34840
#> s_008um_00124_00223-1             120.25401             155.32398
#> s_008um_00131_00230-1             182.41097              98.94860
#> s_008um_00133_00224-1             191.98047             149.44326
#>                       s_008um_00121_00219-1 s_008um_00128_00222-1
#> s_008um_00110_00228-1             113.69103             151.77379
#> s_008um_00122_00239-1             160.19162             144.21288
#> s_008um_00125_00234-1             124.18709              98.94866
#> s_008um_00124_00223-1              39.99757              32.98145
#> s_008um_00131_00230-1             118.92078              68.34847
#> s_008um_00133_00224-1             103.99089              43.07751
#>                       s_008um_00134_00238-1 s_008um_00126_00229-1
#> s_008um_00110_00228-1             207.98165             128.23685
#> s_008um_00122_00239-1              96.32280              86.15696
#> s_008um_00125_00234-1              78.78399              40.78979
#> s_008um_00124_00223-1             144.21351              50.59384
#> s_008um_00131_00230-1              68.34842              40.78823
#> s_008um_00133_00224-1             112.27959              68.81218
#>                       s_008um_00124_00230-1 s_008um_00118_00245-1
#> s_008um_00110_00228-1             113.12595             150.29811
#> s_008um_00122_00239-1              73.75200              57.68436
#> s_008um_00125_00234-1              32.98316             104.29933
#> s_008um_00124_00223-1              55.99709             182.41696
#> s_008um_00131_00230-1              55.99430             158.78225
#> s_008um_00133_00224-1              86.52504             206.43969
#>                       s_008um_00129_00233-1 s_008um_00113_00231-1
#> s_008um_00110_00228-1             157.16024              33.93882
#> s_008um_00122_00239-1              73.74969              96.32589
#> s_008um_00125_00234-1              32.98144              98.94515
#> s_008um_00124_00223-1              89.43782             108.80159
#> s_008um_00131_00230-1              28.84222             144.20722
#> s_008um_00133_00224-1              78.78559             169.49966
#>                       s_008um_00111_00230-1 s_008um_00119_00231-1
#> s_008um_00110_00228-1              17.88756              75.88771
#> s_008um_00122_00239-1             113.69302              68.34842
#> s_008um_00125_00234-1             116.47087              53.66108
#> s_008um_00124_00223-1             118.10695              75.46624
#> s_008um_00131_00230-1             159.98368              96.32283
#> s_008um_00133_00224-1             182.40927             125.20740
#>                       s_008um_00114_00221-1 s_008um_00135_00237-1
#> s_008um_00110_00228-1              64.49339             212.54604
#> s_008um_00122_00239-1             157.57325             105.21266
#> s_008um_00125_00234-1             136.22639              83.51469
#> s_008um_00124_00223-1              81.57646             142.42706
#> s_008um_00131_00230-1             153.87026              64.49439
#> s_008um_00133_00224-1             153.86806             105.21823
#>                       s_008um_00128_00246-1 s_008um_00131_00218-1
#> s_008um_00110_00228-1             203.63282             186.05673
#> s_008um_00122_00239-1              73.75155             182.76641
#> s_008um_00125_00234-1              98.94940             136.69531
#> s_008um_00124_00223-1             186.75233              68.81220
#> s_008um_00131_00230-1             130.22301              95.99504
#> s_008um_00133_00224-1             180.47757              50.59386
#>                       s_008um_00131_00246-1 s_008um_00130_00232-1
#> s_008um_00110_00228-1             221.25307             163.15287
#> s_008um_00122_00239-1              91.20719              85.03353
#> s_008um_00125_00234-1             107.32528              43.07695
#> s_008um_00124_00223-1             192.32307              86.52813
#> s_008um_00131_00230-1             127.99321              17.88730
#> s_008um_00133_00224-1             176.71610              68.34765
#>                       s_008um_00125_00229-1 s_008um_00134_00224-1
#> s_008um_00110_00228-1             120.25428             194.62828
#> s_008um_00122_00239-1              83.51728             153.66260
#> s_008um_00125_00234-1              39.99790             107.62003
#> s_008um_00124_00223-1              48.65965              80.39103
#> s_008um_00131_00230-1              48.65736              53.66193
#> s_008um_00133_00224-1              75.46462               7.99919
#>                       s_008um_00133_00226-1 s_008um_00125_00246-1
#> s_008um_00110_00228-1             184.67531             187.43397
#> s_008um_00122_00239-1             136.22391              60.92287
#> s_008um_00125_00234-1              90.50188              95.99488
#> s_008um_00124_00223-1              75.88775             184.16424
#> s_008um_00131_00230-1              35.77462             136.69516
#> s_008um_00133_00224-1              15.99917             187.26315
#>                       s_008um_00130_00237-1 s_008um_00130_00240-1
#> s_008um_00110_00228-1             175.43846             186.57536
#> s_008um_00122_00239-1              65.96285              64.49166
#> s_008um_00125_00234-1              46.64384              62.47799
#> s_008um_00124_00223-1             121.84586             144.21452
#> s_008um_00131_00230-1              56.56537              80.39458
#> s_008um_00133_00224-1             106.72704             130.22309
#>                       s_008um_00128_00236-1 s_008um_00118_00243-1
#> s_008um_00110_00228-1             157.56800             135.99236
#> s_008um_00122_00239-1              53.66028              45.25088
#> s_008um_00125_00234-1              28.84215              91.20667
#> s_008um_00124_00223-1             108.80616             167.03457
#> s_008um_00131_00230-1              53.66189             147.06545
#> s_008um_00133_00224-1             103.99314             193.64390
#>                       s_008um_00114_00232-1 s_008um_00111_00233-1
#> s_008um_00110_00228-1              45.25176              40.79008
#> s_008um_00122_00239-1              85.03507             100.23137
#> s_008um_00125_00234-1              89.43401             112.27405
#> s_008um_00124_00223-1             107.61943             131.19762
#> s_008um_00131_00230-1             136.92378             161.77321
#> s_008um_00133_00224-1             164.90759             190.13859
#>                       s_008um_00121_00221-1 s_008um_00108_00228-1
#> s_008um_00110_00228-1             104.29723              15.99836
#> s_008um_00122_00239-1             144.21462             142.42536
#> s_008um_00125_00234-1             108.80618             144.20895
#> s_008um_00124_00223-1              28.84217             134.09065
#> s_008um_00131_00230-1             107.62142             184.67587
#> s_008um_00133_00224-1              98.94521             202.52287
#>                       s_008um_00126_00233-1 s_008um_00125_00245-1
#> s_008um_00110_00228-1             134.09205             181.36068
#> s_008um_00122_00239-1              57.68440              53.66263
#> s_008um_00125_00234-1              11.31273              87.99531
#> s_008um_00124_00223-1              81.58019             176.17256
#> s_008um_00131_00230-1              46.64310             129.23542
#> s_008um_00133_00224-1              91.20678             179.76596
#>                       s_008um_00117_00223-1 s_008um_00110_00222-1
#> s_008um_00110_00228-1              68.81213               47.9975
#> s_008um_00122_00239-1             134.09751              166.4592
#> s_008um_00125_00234-1             108.80516              153.6637
#> s_008um_00124_00223-1              55.99431              112.2741
#> s_008um_00131_00230-1             125.20923              179.7616
#> s_008um_00133_00224-1             128.23690              184.6759
#>                       s_008um_00129_00235-1 s_008um_00134_00237-1
#> s_008um_00110_00228-1             161.97305             205.03765
#> s_008um_00122_00239-1              64.49174              97.31410
#> s_008um_00125_00234-1              32.98172              75.88771
#> s_008um_00124_00223-1             103.99448             137.62888
#> s_008um_00131_00230-1              43.07849              60.92291
#> s_008um_00133_00224-1              93.63163             104.30190
#>                       s_008um_00107_00237-1 s_008um_00117_00232-1
#> s_008um_00110_00228-1              75.88984              64.49278
#> s_008um_00122_00239-1             121.04996              68.81442
#> s_008um_00125_00234-1             145.97110              65.96343
#> s_008um_00124_00223-1             176.16565              91.20675
#> s_008um_00131_00230-1             199.97934             113.12537
#> s_008um_00133_00224-1             232.52793             143.09416
#>                       s_008um_00129_00242-1 s_008um_00129_00230-1
#> s_008um_00110_00228-1             188.79243             152.82458
#> s_008um_00122_00239-1              60.92082              91.20672
#> s_008um_00125_00234-1              71.55020              45.25093
#> s_008um_00124_00223-1             157.16700              68.81446
#> s_008um_00131_00230-1              97.31864              15.99837
#> s_008um_00133_00224-1             147.50406              57.68447
#>                       s_008um_00136_00233-1 s_008um_00126_00234-1
#> s_008um_00110_00228-1             211.79074            136.691771
#> s_008um_00122_00239-1             121.84007             51.220837
#> s_008um_00125_00234-1              88.35378              7.999184
#> s_008um_00124_00223-1             124.95494             89.438194
#> s_008um_00131_00230-1              46.64385             51.220311
#> s_008um_00133_00224-1              75.89074             97.644933
#>                       s_008um_00135_00234-1 s_008um_00129_00222-1
#> s_008um_00110_00228-1             205.65980             159.38252
#> s_008um_00122_00239-1             111.41576             147.06851
#> s_008um_00125_00234-1              79.99185             101.18656
#> s_008um_00124_00223-1             124.44234              40.78795
#> s_008um_00131_00230-1              45.25175              65.96635
#> s_008um_00133_00224-1              81.58018              35.77407
#>                       s_008um_00129_00227-1 s_008um_00132_00231-1
#> s_008um_00110_00228-1             152.19474             177.61132
#> s_008um_00122_00239-1             111.13143             102.44059
#> s_008um_00125_00234-1              64.49339              60.92005
#> s_008um_00124_00223-1              51.22124              90.50353
#> s_008um_00131_00230-1              28.84271              11.31294
#> s_008um_00133_00224-1              39.99631              56.56540
#>                       s_008um_00114_00226-1 s_008um_00122_00222-1
#> s_008um_00110_00228-1              35.77352             107.32060
#> s_008um_00122_00239-1             122.10762             135.99287
#> s_008um_00125_00234-1             108.80349              98.94951
#> s_008um_00124_00223-1              83.51387              17.88704
#> s_008um_00131_00230-1             139.70070              96.32595
#> s_008um_00133_00224-1             152.82404              89.43407
#>                       s_008um_00127_00233-1 s_008um_00136_00227-1
#> s_008um_00110_00228-1             141.74716             208.13247
#> s_008um_00122_00239-1              62.47687             147.49944
#> s_008um_00125_00234-1              17.88677             104.29726
#> s_008um_00124_00223-1              83.51817             101.18366
#> s_008um_00131_00230-1              39.99629              46.64312
#> s_008um_00133_00224-1              86.52668              33.93883
#>                       s_008um_00132_00225-1 s_008um_00136_00245-1
#> s_008um_00110_00228-1             177.61047              248.4960
#> s_008um_00122_00239-1             137.62650              121.8416
#> s_008um_00125_00234-1              91.20677              124.4423
#> s_008um_00124_00223-1              65.96347              200.4681
#> s_008um_00131_00230-1              40.78982              126.4845
#> s_008um_00133_00224-1              11.31274              169.6970
#>                       s_008um_00115_00233-1 s_008um_00122_00229-1
#> s_008um_00110_00228-1              56.56470              96.32311
#> s_008um_00122_00239-1              73.75103              79.99578
#> s_008um_00125_00234-1              80.39098              46.64493
#> s_008um_00124_00223-1             107.61999              50.59328
#> s_008um_00131_00230-1             130.21707              72.43590
#> s_008um_00133_00224-1             160.98092              96.65471
#>                       s_008um_00133_00225-1 s_008um_00121_00227-1
#> s_008um_00110_00228-1            185.539444              88.35376
#> s_008um_00122_00239-1            142.424531              96.32779
#> s_008um_00125_00234-1             96.324757              64.49440
#> s_008um_00124_00223-1             73.749326              39.99686
#> s_008um_00131_00230-1             43.078518              83.51471
#> s_008um_00133_00224-1              7.999586              98.94435
#>                       s_008um_00136_00246-1 s_008um_00126_00220-1
#> s_008um_00110_00228-1              252.9626             143.09415
#> s_008um_00122_00239-1              125.2091             155.32288
#> s_008um_00125_00234-1              130.2219             112.27933
#> s_008um_00124_00223-1              207.5264              28.84224
#> s_008um_00131_00230-1              134.0974              89.43784
#> s_008um_00133_00224-1              177.6197              64.49281
#>                       s_008um_00115_00237-1 s_008um_00128_00232-1
#> s_008um_00110_00228-1              82.36039             147.49858
#> s_008um_00122_00239-1              58.23542              73.75025
#> s_008um_00125_00234-1              83.51382              28.84166
#> s_008um_00124_00223-1             133.13650              78.78664
#> s_008um_00131_00230-1             139.69990              28.84167
#> s_008um_00133_00224-1             177.61220              75.46626
#>                       s_008um_00131_00224-1 s_008um_00113_00234-1
#> s_008um_00110_00228-1             171.00278              53.66268
#> s_008um_00122_00239-1             139.93255              82.35822
#> s_008um_00125_00234-1              93.28839              95.99019
#> s_008um_00124_00223-1              56.56300             124.44004
#> s_008um_00131_00230-1              47.99750             147.49743
#> s_008um_00133_00224-1              15.99838             178.86768
#>                       s_008um_00108_00226-1 s_008um_00135_00223-1
#> s_008um_00110_00228-1              22.62588             203.93971
#> s_008um_00122_00239-1             152.82909             164.91088
#> s_008um_00125_00234-1             150.29344             118.91862
#> s_008um_00124_00223-1             130.21708              87.99108
#> s_008um_00131_00230-1             186.74370              64.49343
#> s_008um_00133_00224-1             200.61833              17.88678
#>                       s_008um_00117_00241-1 s_008um_00137_00227-1
#> s_008um_00110_00228-1             118.11195             216.12597
#> s_008um_00122_00239-1              43.07692             153.66093
#> s_008um_00125_00234-1              85.03350             111.12877
#> s_008um_00124_00223-1             154.49556             108.80174
#> s_008um_00131_00230-1             142.42281              53.66033
#> s_008um_00133_00224-1             186.74602              39.99700
#>                       s_008um_00137_00244-1 s_008um_00134_00234-1
#> s_008um_00110_00228-1              251.0573             197.89032
#> s_008um_00122_00239-1              126.4795             103.98947
#> s_008um_00125_00234-1              124.9549              71.99266
#> s_008um_00124_00223-1              197.5739             118.92075
#> s_008um_00131_00230-1              121.8458              39.99754
#> s_008um_00133_00224-1              163.1603              80.39492
#>                       s_008um_00137_00245-1 s_008um_00120_00243-1
#> s_008um_00110_00228-1              255.2285             144.21346
#> s_008um_00122_00239-1              129.2324              35.77456
#> s_008um_00125_00234-1              130.2214              82.35906
#> s_008um_00124_00223-1              204.4192             163.15914
#> s_008um_00131_00230-1              129.2370             136.22385
#> s_008um_00133_00224-1              171.0117             184.15967
#>                       s_008um_00124_00218-1 s_008um_00117_00237-1
#> s_008um_00110_00228-1             137.62431              91.20835
#> s_008um_00122_00239-1             168.75100              43.07748
#> s_008um_00125_00234-1             128.24321              68.34504
#> s_008um_00124_00223-1              39.99794             125.21108
#> s_008um_00131_00230-1             111.13327             125.20734
#> s_008um_00133_00224-1              86.52651             164.90919
#>                       s_008um_00126_00237-1 s_008um_00119_00230-1
#> s_008um_00110_00228-1             146.84839              73.74929
#> s_008um_00122_00239-1              35.77352              75.89070
#> s_008um_00125_00234-1              25.29690              57.68430
#> s_008um_00124_00223-1             113.13134              68.81326
#> s_008um_00131_00230-1              68.81324              95.99022
#> s_008um_00133_00224-1             118.11020             121.84012
#>                       s_008um_00133_00228-1 s_008um_00115_00218-1
#> s_008um_00110_00228-1             183.98126              89.43651
#> s_008um_00122_00239-1             124.44004             177.07839
#> s_008um_00125_00234-1              79.99259             150.93498
#> s_008um_00124_00223-1              82.35827              82.35829
#> s_008um_00131_00230-1              22.62548             159.98801
#> s_008um_00133_00224-1              31.99834             151.77551
#>                       s_008um_00116_00226-1 s_008um_00130_00228-1
#> s_008um_00110_00228-1              50.59124             159.98369
#> s_008um_00122_00239-1             114.53635             108.80323
#> s_008um_00125_00234-1              96.32592              62.47690
#> s_008um_00124_00223-1              68.34508              62.47748
#> s_008um_00131_00230-1             124.18173              17.88756
#> s_008um_00133_00224-1             136.92383              39.99687
#>                       s_008um_00117_00221-1 s_008um_00123_00225-1
#> s_008um_00110_00228-1              79.18912             106.72226
#> s_008um_00122_00239-1             149.44468             112.27927
#> s_008um_00125_00234-1             122.10766              73.75261
#> s_008um_00124_00223-1              58.23546              17.88731
#> s_008um_00131_00230-1             133.13604              75.46584
#> s_008um_00133_00224-1             130.21799              80.39074
#>                       s_008um_00120_00235-1 s_008um_00116_00237-1
#> s_008um_00110_00228-1              97.64491              86.52810
#> s_008um_00122_00239-1              35.77510              50.59179
#> s_008um_00125_00234-1              40.78792              75.88686
#> s_008um_00124_00223-1             101.18653             128.98676
#> s_008um_00131_00230-1              96.65466             132.41028
#> s_008um_00133_00224-1             136.22282             171.19165
#>                       s_008um_00135_00246-1 s_008um_00129_00236-1
#> s_008um_00110_00228-1              246.4278             164.90971
#> s_008um_00122_00239-1              118.1087              60.92002
#> s_008um_00125_00234-1              124.9560              35.77405
#> s_008um_00124_00223-1              203.9496             111.42125
#> s_008um_00131_00230-1              131.9326              50.59326
#> s_008um_00133_00224-1              176.7167             101.18655
#>                       s_008um_00110_00219-1 s_008um_00134_00241-1
#> s_008um_00110_00228-1              71.99626             218.33933
#> s_008um_00122_00239-1             186.57976              97.31467
#> s_008um_00125_00234-1             169.69413              91.20721
#> s_008um_00124_00223-1             116.47092             164.72078
#> s_008um_00131_00230-1             189.63649              91.20933
#> s_008um_00133_00224-1             188.27965             136.22806
#>                       s_008um_00119_00238-1 s_008um_00135_00220-1
#> s_008um_00110_00228-1             107.62193             209.96899
#> s_008um_00122_00239-1              25.29590             184.15975
#> s_008um_00125_00234-1              57.68331             137.62657
#> s_008um_00124_00223-1             126.48315              91.20469
#> s_008um_00131_00230-1             115.36664              86.15706
#> s_008um_00133_00224-1             158.37826              35.77464
#>                       s_008um_00123_00229-1 s_008um_00118_00235-1
#> s_008um_00110_00228-1             104.29677              85.03509
#> s_008um_00122_00239-1              80.39458              45.25174
#> s_008um_00125_00234-1              43.07903              56.56267
#> s_008um_00124_00223-1              48.65936             107.32379
#> s_008um_00131_00230-1              64.49169             111.41577
#> s_008um_00133_00224-1              89.43387             148.79473
#>                       s_008um_00131_00242-1 s_008um_00112_00232-1
#> s_008um_00110_00228-1             201.89502              35.77512
#> s_008um_00122_00239-1              75.88769              97.64489
#> s_008um_00125_00234-1              79.99504             105.21323
#> s_008um_00124_00223-1             161.97914             119.98885
#> s_008um_00131_00230-1              95.99493             152.82398
#> s_008um_00133_00224-1             144.87818             179.75937
#>                       s_008um_00121_00248-1 s_008um_00112_00223-1
#> s_008um_00110_00228-1              182.5930              43.07850
#> s_008um_00122_00239-1               72.4390             150.93492
#> s_008um_00125_00234-1              116.4745             136.22526
#> s_008um_00124_00223-1              201.4236              95.99023
#> s_008um_00131_00230-1              164.7181             161.97309
#> s_008um_00133_00224-1              214.6475             168.17344
#>                       s_008um_00123_00224-1 s_008um_00133_00222-1
#> s_008um_00110_00228-1             108.80057             190.13824
#> s_008um_00122_00239-1             120.25988             161.97547
#> s_008um_00125_00234-1              81.58018             115.36891
#> s_008um_00124_00223-1              11.31274              72.43564
#> s_008um_00131_00230-1              79.99399              65.96580
#> s_008um_00133_00224-1              79.99188              15.99917
#>                       s_008um_00122_00223-1 s_008um_00129_00241-1
#> s_008um_00110_00228-1             103.98948             184.15950
#> s_008um_00122_00239-1             127.99328              58.23542
#> s_008um_00125_00234-1              91.20938              64.49437
#> s_008um_00124_00223-1              15.99837             149.44466
#> s_008um_00131_00230-1              91.20727              89.43757
#> s_008um_00133_00224-1              88.35410             139.70574
#>                       s_008um_00126_00242-1 s_008um_00128_00241-1
#> s_008um_00110_00228-1             170.07015             177.61524
#> s_008um_00122_00239-1              39.99696              50.59179
#> s_008um_00125_00234-1              64.49473              60.92289
#> s_008um_00124_00223-1             152.83196             147.50519
#> s_008um_00131_00230-1             103.99307              91.20849
#> s_008um_00133_00224-1             154.49560             141.75167
#>                       s_008um_00124_00248-1 s_008um_00136_00230-1
#> s_008um_00110_00228-1             195.29305             208.59358
#> s_008um_00122_00239-1              73.75252             133.13378
#> s_008um_00125_00234-1             112.27918              93.62807
#> s_008um_00124_00223-1             199.98942             111.13053
#> s_008um_00131_00230-1             154.49550              39.99594
#> s_008um_00133_00224-1             205.04278              53.66269
#>                       s_008um_00137_00236-1 s_008um_00119_00236-1
#> s_008um_00110_00228-1             225.26109              96.32591
#> s_008um_00122_00239-1             122.36378              33.93880
#> s_008um_00125_00234-1              97.31470              50.59124
#> s_008um_00124_00223-1             147.06822             111.41987
#> s_008um_00131_00230-1              67.87762             107.32059
#> s_008um_00133_00224-1             101.18764             147.49946
#>                       s_008um_00132_00222-1 s_008um_00131_00221-1
#> s_008um_00110_00228-1             182.40929             177.06944
#> s_008um_00122_00239-1             157.77314             160.98571
#> s_008um_00125_00234-1             111.13149             114.53482
#> s_008um_00124_00223-1              64.49143              58.23492
#> s_008um_00131_00230-1              64.49452              71.99627
#> s_008um_00133_00224-1              17.88757              28.84272
#>                       s_008um_00128_00244-1 s_008um_00118_00221-1
#> s_008um_00110_00228-1             192.65177              85.03355
#> s_008um_00122_00239-1              62.47742             147.50521
#> s_008um_00125_00234-1              83.51809             118.11201
#> s_008um_00124_00223-1             171.01174              50.59183
#> s_008um_00131_00230-1             114.53583             126.48136
#> s_008um_00133_00224-1             164.91436             122.36471
#>                       s_008um_00122_00247-1 s_008um_00133_00240-1
#> s_008um_00110_00228-1             179.76707             207.52051
#> s_008um_00122_00239-1              63.99657              88.35404
#> s_008um_00125_00234-1             106.72692              79.99395
#> s_008um_00124_00223-1             192.65497             153.87449
#> s_008um_00131_00230-1             153.87208              81.58014
#> s_008um_00133_00224-1             203.94669             127.99329
#>                       s_008um_00119_00245-1 s_008um_00124_00235-1
#> s_008um_00110_00228-1             153.87443             125.20919
#> s_008um_00122_00239-1              53.66183              35.77457
#> s_008um_00125_00234-1             100.23246              11.31273
#> s_008um_00124_00223-1             180.47754              95.99498
#> s_008um_00131_00230-1             153.66250              68.81215
#> s_008um_00133_00224-1             201.89545             113.69216
#>                       s_008um_00123_00231-1 s_008um_00122_00246-1
#> s_008um_00110_00228-1             106.72312             173.05614
#> s_008um_00122_00239-1              64.49446              55.99700
#> s_008um_00125_00234-1              28.84270              98.94854
#> s_008um_00124_00223-1              64.49451             184.68423
#> s_008um_00131_00230-1              64.49140             146.84980
#> s_008um_00133_00224-1              97.64328             196.76022
#>                       s_008um_00117_00229-1 s_008um_00116_00238-1
#> s_008um_00110_00228-1              56.56297              93.28985
#> s_008um_00122_00239-1              89.43778              48.65733
#> s_008um_00125_00234-1              75.46582              78.78290
#> s_008um_00124_00223-1              73.74973             135.99033
#> s_008um_00131_00230-1             112.27409             135.98656
#> s_008um_00133_00224-1             134.09070             176.16571
#>                       s_008um_00122_00237-1 s_008um_00132_00223-1
#> s_008um_00110_00228-1             119.99095             180.46958
#> s_008um_00122_00239-1              15.99915             150.93246
#> s_008um_00125_00234-1              33.93818             104.29946
#> s_008um_00124_00223-1             113.13076              63.99351
#> s_008um_00131_00230-1              91.20562              56.56541
#> s_008um_00133_00224-1             136.22393              11.31294
#>                       s_008um_00133_00247-1 s_008um_00137_00226-1
#> s_008um_00110_00228-1              238.6455             216.56951
#> s_008um_00122_00239-1              108.8034             158.78123
#> s_008um_00125_00234-1              122.1075             115.36671
#> s_008um_00124_00223-1              205.0452             106.72317
#> s_008um_00131_00230-1              136.9309              57.68337
#> s_008um_00133_00224-1              183.9903              35.77407
#>                       s_008um_00124_00231-1 s_008um_00128_00229-1
#> s_008um_00110_00228-1             114.53156             144.20751
#> s_008um_00122_00239-1              65.96573              93.28834
#> s_008um_00125_00234-1              25.29690              46.64418
#> s_008um_00124_00223-1              63.99667              57.68542
#> s_008um_00131_00230-1              56.56270              25.29591
#> s_008um_00133_00224-1              91.20567              56.56369
#>                       s_008um_00120_00234-1 s_008um_00122_00225-1
#> s_008um_00110_00228-1              93.28769              98.94430
#> s_008um_00122_00239-1              43.07902             111.99411
#> s_008um_00125_00234-1              39.99592              75.89073
#> s_008um_00124_00223-1              93.63161              22.62547
#> s_008um_00131_00230-1              93.62805              82.35826
#> s_008um_00133_00224-1             131.19767              88.35381
#>                       s_008um_00129_00237-1 s_008um_00137_00228-1
#> s_008um_00110_00228-1             168.17592             215.97801
#> s_008um_00122_00239-1              58.23486             148.79472
#> s_008um_00125_00234-1              39.99698             107.32063
#> s_008um_00124_00223-1             118.92234             111.41718
#> s_008um_00131_00230-1              58.23732              50.59129
#> s_008um_00133_00224-1             108.80506              45.25177
#>                       s_008um_00109_00240-1 s_008um_00126_00225-1
#> s_008um_00110_00228-1              96.32747             130.21708
#> s_008um_00122_00239-1             104.29642             116.47464
#> s_008um_00125_00234-1             136.69005              72.43910
#> s_008um_00124_00223-1             181.35738              22.62589
#> s_008um_00131_00230-1             193.30925              56.56471
#> s_008um_00133_00224-1             230.73327              56.56272
#>                       s_008um_00119_00239-1 s_008um_00128_00231-1
#> s_008um_00110_00228-1             113.69414             145.97204
#> s_008um_00122_00239-1              23.99754              79.99365
#> s_008um_00125_00234-1              62.47630              33.93819
#> s_008um_00124_00223-1             134.09610              71.55026
#> s_008um_00131_00230-1             119.98883              25.29564
#> s_008um_00133_00224-1             164.13239              68.81329
#>                       s_008um_00132_00221-1 s_008um_00128_00238-1
#> s_008um_00110_00228-1             184.67542             164.71647
#> s_008um_00122_00239-1             164.71827              48.65704
#> s_008um_00125_00234-1             118.11023              39.99753
#> s_008um_00124_00223-1              65.96292             124.18705
#> s_008um_00131_00230-1              72.43914              68.34761
#> s_008um_00133_00224-1              25.29693             118.92098
#>                       s_008um_00124_00228-1 s_008um_00136_00239-1
#> s_008um_00110_00228-1             111.98858             225.82964
#> s_008um_00122_00239-1              89.43757             111.98856
#> s_008um_00125_00234-1              48.65963              96.65598
#> s_008um_00124_00223-1              39.99792             159.99016
#> s_008um_00131_00230-1              58.23545              82.36038
#> s_008um_00133_00224-1              78.78298             122.37025
#>                       s_008um_00137_00225-1 s_008um_00134_00235-1
#> s_008um_00110_00228-1             217.30683             199.98136
#> s_008um_00122_00239-1             164.13186             101.18250
#> s_008um_00125_00234-1             119.98890              72.43588
#> s_008um_00124_00223-1             105.21331             124.95605
#> s_008um_00131_00230-1              62.47638              46.64493
#> s_008um_00133_00224-1              32.98174              88.35838
#>                       s_008um_00134_00231-1 s_008um_00109_00229-1
#> s_008um_00110_00228-1             193.47505              11.31273
#> s_008um_00122_00239-1             115.36665             131.19993
#> s_008um_00125_00234-1              75.88690             134.09204
#> s_008um_00124_00223-1             102.44246             129.23084
#> s_008um_00131_00230-1              25.29591             176.16392
#> s_008um_00133_00224-1              56.56569             196.10213
#>                       s_008um_00116_00239-1 s_008um_00113_00223-1
#> s_008um_00110_00228-1             100.23407              46.64418
#> s_008um_00122_00239-1              47.99508             146.85218
#> s_008um_00125_00234-1              82.35692             130.22144
#> s_008um_00124_00223-1             143.09836              87.99105
#> s_008um_00131_00230-1             139.92925             154.49190
#> s_008um_00133_00224-1             181.35633             160.18376
#>                       s_008um_00121_00246-1 s_008um_00121_00234-1
#> s_008um_00110_00228-1             168.75036             100.23140
#> s_008um_00122_00239-1              56.56531              40.79006
#> s_008um_00125_00234-1             101.18643              31.99673
#> s_008um_00124_00223-1             185.54822              91.20853
#> s_008um_00131_00230-1             150.93236              86.15390
#> s_008um_00133_00224-1             200.46504             124.95270
#>                       s_008um_00135_00224-1 s_008um_00124_00241-1
#> s_008um_00110_00228-1             202.52289             152.82907
#> s_008um_00122_00239-1             158.78235              22.62586
#> s_008um_00125_00234-1             113.12736              56.56534
#> s_008um_00124_00223-1              88.35411             143.99243
#> s_008um_00131_00230-1              57.68447             104.29939
#> s_008um_00133_00224-1              15.99838             153.87217
#>                       s_008um_00123_00232-1 s_008um_00127_00246-1
#> s_008um_00110_00228-1             108.80169             198.05742
#> s_008um_00122_00239-1              56.56535              68.81438
#> s_008um_00125_00234-1              22.62587              97.31918
#> s_008um_00124_00223-1              72.43911             185.54911
#> s_008um_00131_00230-1              65.96288             131.93144
#> s_008um_00133_00224-1             102.44065             182.41699
#>                       s_008um_00130_00247-1 s_008um_00125_00221-1
#> s_008um_00110_00228-1             220.67444             132.41032
#> s_008um_00122_00239-1              90.50344             145.97802
#> s_008um_00125_00234-1             111.42115             103.99458
#> s_008um_00124_00223-1             197.89890              17.88731
#> s_008um_00131_00230-1             136.22769              86.52814
#> s_008um_00133_00224-1             185.54824              68.34592
#>                       s_008um_00120_00222-1 s_008um_00134_00229-1
#> s_008um_00110_00228-1              93.28619             192.14718
#> s_008um_00122_00239-1             136.93096             124.95266
#> s_008um_00125_00234-1             103.99448              82.35698
#> s_008um_00124_00223-1              32.98173              93.28772
#> s_008um_00131_00230-1             108.80351              25.29564
#> s_008um_00133_00224-1             105.21330              40.79010
#>                       s_008um_00123_00221-1 s_008um_00125_00239-1
#> s_008um_00110_00228-1             118.10696             148.79728
#> s_008um_00122_00239-1             144.21433              23.99754
#> s_008um_00125_00234-1             105.21825              39.99788
#> s_008um_00124_00223-1              17.88757             128.24315
#> s_008um_00131_00230-1              96.32651              86.52663
#> s_008um_00133_00224-1              83.51474             135.99036
#>                       s_008um_00134_00220-1 s_008um_00133_00245-1
#> s_008um_00110_00228-1             202.36509              228.7882
#> s_008um_00122_00239-1             179.76424              100.2313
#> s_008um_00125_00234-1             133.13659              108.8051
#> s_008um_00124_00223-1              83.51392              190.1477
#> s_008um_00131_00230-1              83.51738              121.0557
#> s_008um_00133_00224-1              32.98291              167.9912
#>                       s_008um_00124_00221-1 s_008um_00133_00242-1
#> s_008um_00110_00228-1             125.20737             215.38922
#> s_008um_00122_00239-1             144.87819              91.20544
#> s_008um_00125_00234-1             104.30192              90.50347
#> s_008um_00124_00223-1              15.99917             168.18119
#> s_008um_00131_00230-1              91.20839              97.31922
#> s_008um_00133_00224-1              75.88776             143.99244
#>                       s_008um_00106_00222-1 s_008um_00111_00224-1
#> s_008um_00110_00228-1              57.68543              32.98288
#> s_008um_00122_00239-1             186.74946             148.79952
#> s_008um_00125_00234-1             179.76336             137.62668
#> s_008um_00124_00223-1             144.20754             104.29651
#> s_008um_00131_00230-1             209.97118             167.02942
#> s_008um_00133_00224-1             216.57011             175.98211
#>                       s_008um_00111_00227-1 s_008um_00118_00231-1
#> s_008um_00110_00228-1              11.31273              68.34589
#> s_008um_00122_00239-1             130.22196              71.55021
#> s_008um_00125_00234-1             125.20919              60.92084
#> s_008um_00124_00223-1             108.80058              79.99369
#> s_008um_00131_00230-1             161.77411             104.29649
#> s_008um_00133_00224-1             177.61048             132.41034
#>                       s_008um_00123_00243-1 s_008um_00135_00248-1
#> s_008um_00110_00228-1             158.78516              256.1060
#> s_008um_00122_00239-1              32.98313              126.4812
#> s_008um_00125_00234-1              73.75198              137.6288
#> s_008um_00124_00223-1             160.19127              218.4922
#> s_008um_00131_00230-1             122.10559              147.5051
#> s_008um_00133_00224-1             171.75512              192.6556
#>                       s_008um_00108_00220-1 s_008um_00119_00227-1
#> s_008um_00110_00228-1              65.96636              72.43558
#> s_008um_00122_00239-1             188.79526              98.94946
#> s_008um_00125_00234-1             176.16891              73.75161
#> s_008um_00124_00223-1             130.21797              51.22032
#> s_008um_00131_00230-1             200.62150              98.94518
#> s_008um_00133_00224-1             202.52407             114.53075
#>                       s_008um_00119_00237-1 s_008um_00126_00231-1
#> s_008um_00110_00228-1             101.81644             130.21793
#> s_008um_00122_00239-1              28.84214              71.54916
#> s_008um_00125_00234-1              53.66028              25.29663
#> s_008um_00124_00223-1             118.92096              65.96634
#> s_008um_00131_00230-1             111.12872              40.78794
#> s_008um_00133_00224-1             152.82633              79.18916
#>                       s_008um_00130_00239-1 s_008um_00125_00235-1
#> s_008um_00110_00228-1             182.58826            132.412153
#> s_008um_00122_00239-1              63.99346             39.996816
#> s_008um_00125_00234-1              56.56467              7.999578
#> s_008um_00124_00223-1             136.69688             96.327834
#> s_008um_00131_00230-1              72.43908             62.476338
#> s_008um_00133_00224-1             122.36940            108.803283
#>                       s_008um_00124_00234-1 s_008um_00122_00244-1
#> s_008um_00110_00228-1            121.841682             159.99011
#> s_008um_00122_00239-1             43.078469              39.99786
#> s_008um_00125_00234-1              7.999184              83.51724
#> s_008um_00124_00223-1             87.995404             168.75092
#> s_008um_00131_00230-1             64.491771             133.13646
#> s_008um_00133_00224-1            107.620023             182.59028
#>                       s_008um_00131_00220-1 s_008um_00125_00240-1
#> s_008um_00110_00228-1             179.75939             153.66363
#> s_008um_00122_00239-1             168.17887              25.29590
#> s_008um_00125_00234-1             121.84430              47.99746
#> s_008um_00124_00223-1              60.92008             136.22806
#> s_008um_00131_00230-1              79.99586              93.28834
#> s_008um_00133_00224-1              35.77514             143.09839
#>                       s_008um_00134_00236-1 s_008um_00119_00240-1
#> s_008um_00110_00228-1             202.36724             119.99260
#> s_008um_00122_00239-1              98.94429              25.29561
#> s_008um_00125_00234-1              73.74929              67.87635
#> s_008um_00124_00223-1             131.20163             141.75165
#> s_008um_00131_00230-1              53.66267             124.95263
#> s_008um_00133_00224-1              96.32783             170.06822
#>                       s_008um_00119_00221-1 s_008um_00132_00224-1
#> s_008um_00110_00228-1              91.20563            178.866936
#> s_008um_00122_00239-1             145.97889            144.211082
#> s_008um_00125_00234-1             114.53639             97.644928
#> s_008um_00124_00223-1              43.07751             64.491711
#> s_008um_00131_00230-1             119.99100             48.659365
#> s_008um_00133_00224-1             114.53162              7.999189
#>                       s_008um_00121_00236-1 s_008um_00122_00248-1
#> s_008um_00110_00228-1             108.80347             186.57964
#> s_008um_00122_00239-1              25.29689              71.99614
#> s_008um_00125_00234-1              35.77352             114.53577
#> s_008um_00124_00223-1             106.72703             200.62801
#> s_008um_00131_00230-1              93.28619             160.98557
#> s_008um_00133_00224-1             135.75281             211.19163
#>                       s_008um_00121_00241-1 s_008um_00107_00239-1
#> s_008um_00110_00228-1             136.22633              91.20845
#> s_008um_00122_00239-1              17.88728             119.98769
#> s_008um_00125_00234-1              64.49334             149.43683
#> s_008um_00124_00223-1             145.97799             186.74540
#> s_008um_00131_00230-1             118.91853             205.03512
#> s_008um_00133_00224-1             166.45631             240.10983
#>                       s_008um_00128_00245-1 s_008um_00114_00227-1
#> s_008um_00110_00228-1             198.05687              32.98143
#> s_008um_00122_00239-1              67.87758             115.37079
#> s_008um_00125_00234-1              91.20929             104.29896
#> s_008um_00124_00223-1             178.87630              86.15391
#> s_008um_00131_00230-1             122.36932             138.08799
#> s_008um_00133_00224-1             172.68601             153.86718
#>                       s_008um_00121_00228-1 s_008um_00123_00245-1
#> s_008um_00110_00228-1              87.99102             171.19682
#> s_008um_00122_00239-1              88.35834              48.65958
#> s_008um_00125_00234-1              57.68540              89.43752
#> s_008um_00124_00223-1              46.64420             176.17226
#> s_008um_00131_00230-1              81.57645             135.99028
#> s_008um_00133_00224-1             101.18256             186.06243
#>                       s_008um_00137_00234-1 s_008um_00128_00239-1
#> s_008um_00110_00228-1             221.24788             168.74660
#> s_008um_00122_00239-1             126.47813              47.99509
#> s_008um_00125_00234-1              95.99022              46.64491
#> s_008um_00124_00223-1             136.22527             131.93264
#> s_008um_00131_00230-1              57.68430              75.88988
#> s_008um_00133_00224-1              86.15809             126.48317
#>                       s_008um_00131_00223-1 s_008um_00115_00231-1
#> s_008um_00110_00228-1             172.67843              46.64385
#> s_008um_00122_00239-1             146.84989              85.03563
#> s_008um_00125_00234-1             100.23258              83.51469
#> s_008um_00124_00223-1              55.99432              96.32417
#> s_008um_00131_00230-1              55.99709             128.23656
#> s_008um_00133_00224-1              17.88704             154.48999
#>                       s_008um_00136_00243-1 s_008um_00130_00224-1
#> s_008um_00110_00228-1              240.1136             163.15174
#> s_008um_00122_00239-1              116.4708             135.99035
#> s_008um_00125_00234-1              113.6930              89.43651
#> s_008um_00124_00223-1              186.5797              48.65737
#> s_008um_00131_00230-1              111.4212              48.65965
#> s_008um_00133_00224-1              153.8752              23.99757
#>                       s_008um_00129_00238-1 s_008um_00107_00240-1
#> s_008um_00110_00228-1             171.75289              98.94856
#> s_008um_00122_00239-1              56.56267             120.25390
#> s_008um_00125_00234-1              45.25174             151.77367
#> s_008um_00124_00223-1             126.48455             192.31635
#> s_008um_00131_00230-1              65.96574             207.97887
#> s_008um_00133_00224-1             116.47467             244.20577
#>                       s_008um_00134_00232-1 s_008um_00128_00228-1
#> s_008um_00110_00228-1             194.62940             143.98532
#> s_008um_00122_00239-1             111.12872             100.23253
#> s_008um_00125_00234-1              73.74873              53.66190
#> s_008um_00124_00223-1             107.62141              51.22179
#> s_008um_00131_00230-1              28.84215              28.84216
#> s_008um_00133_00224-1              64.49480              51.22034
#>                       s_008um_00118_00239-1 s_008um_00112_00218-1
#> s_008um_00110_00228-1             108.80512              81.57962
#> s_008um_00122_00239-1              31.99672             186.06515
#> s_008um_00125_00234-1              68.81211             164.91386
#> s_008um_00124_00223-1             136.69522             103.99088
#> s_008um_00131_00230-1             126.47913             179.76340
#> s_008um_00133_00224-1             169.69098             174.70640
#>                       s_008um_00125_00248-1 s_008um_00137_00233-1
#> s_008um_00110_00228-1             199.98761             219.65117
#> s_008um_00122_00239-1              75.89064             129.23084
#> s_008um_00125_00234-1             111.99402              96.32284
#> s_008um_00124_00223-1             200.14948             131.19998
#> s_008um_00131_00230-1             151.77968              53.66109
#> s_008um_00133_00224-1             202.37298              78.78664
#>                       s_008um_00123_00233-1 s_008um_00122_00235-1
#> s_008um_00110_00228-1             111.41713             111.13050
#> s_008um_00122_00239-1              48.65931              31.99830
#> s_008um_00125_00234-1              17.88703              25.29562
#> s_008um_00124_00223-1              80.39462              97.31869
#> s_008um_00131_00230-1              68.34508              82.35697
#> s_008um_00133_00224-1             107.61947             124.44008
#>                       s_008um_00134_00221-1 s_008um_00135_00230-1
#> s_008um_00110_00228-1             199.97946             200.61889
#> s_008um_00122_00239-1             173.05333             126.47915
#> s_008um_00125_00234-1             126.48143              86.15392
#> s_008um_00124_00223-1              81.57592             104.29899
#> s_008um_00131_00230-1              75.88995              31.99675
#> s_008um_00133_00224-1              25.29666              50.59383
#>                       s_008um_00110_00232-1 s_008um_00118_00222-1
#> s_008um_00110_00228-1              31.99832              79.99256
#> s_008um_00122_00239-1             111.13047             139.70687
#> s_008um_00125_00234-1             121.04999             111.13324
#> s_008um_00124_00223-1             133.13377              48.65737
#> s_008um_00131_00230-1             168.74275             122.10494
#> s_008um_00133_00224-1             194.79282             121.05007
#>                       s_008um_00129_00225-1 s_008um_00134_00227-1
#> s_008um_00110_00228-1             153.86715             192.14690
#> s_008um_00122_00239-1             125.21108             135.75278
#> s_008um_00125_00234-1              78.78557              91.20566
#> s_008um_00124_00223-1              43.07751              86.15502
#> s_008um_00131_00230-1              43.07905              33.93821
#> s_008um_00133_00224-1              32.98146              25.29692
#>                       s_008um_00124_00236-1 s_008um_00117_00225-1
#> s_008um_00110_00228-1             128.98555              60.92003
#> s_008um_00122_00239-1              28.84220             118.92232
#> s_008um_00125_00234-1              17.88729              96.32648
#> s_008um_00124_00223-1             103.99456              58.23489
#> s_008um_00131_00230-1              73.74972             118.91780
#> s_008um_00133_00224-1             119.99055             128.23661
#>                       s_008um_00114_00224-1 s_008um_00110_00227-1
#> s_008um_00110_00228-1              45.25092              7.999581
#> s_008um_00122_00239-1             135.99240            135.755247
#> s_008um_00125_00234-1             118.92019            132.412160
#> s_008um_00124_00223-1              80.39072            116.469760
#> s_008um_00131_00230-1             144.20899            169.688937
#> s_008um_00133_00224-1             151.98455            185.539453
#>                       s_008um_00127_00244-1 s_008um_00127_00220-1
#> s_008um_00110_00228-1             186.74883             150.29135
#> s_008um_00122_00239-1              56.56466             157.16563
#> s_008um_00125_00234-1              81.58011             113.13080
#> s_008um_00124_00223-1             169.69695              33.93822
#> s_008um_00131_00230-1             116.47460              86.15812
#> s_008um_00133_00224-1             167.03460              57.68434
#>                       s_008um_00119_00242-1 s_008um_00123_00242-1
#> s_008um_00110_00228-1             133.13870             152.82962
#> s_008um_00122_00239-1              33.93816              25.29689
#> s_008um_00125_00234-1              79.99362              65.96571
#> s_008um_00124_00223-1             157.16557             152.20220
#> s_008um_00131_00230-1             135.75273             115.36882
#> s_008um_00133_00224-1             182.41346             164.71823
#>                       s_008um_00134_00240-1 s_008um_00128_00240-1
#> s_008um_00110_00228-1             214.64430             173.05288
#> s_008um_00122_00239-1              96.32309              48.65733
#> s_008um_00125_00234-1              86.52643              53.66265
#> s_008um_00124_00223-1             157.77563             139.70687
#> s_008um_00131_00230-1              83.51812              83.51729
#> s_008um_00133_00224-1             128.24315             134.09613
#>                       s_008um_00129_00248-1 s_008um_00120_00237-1
#> s_008um_00110_00228-1             220.67499             107.62137
#> s_008um_00122_00239-1              91.20828              22.62587
#> s_008um_00125_00234-1             116.47568              46.64308
#> s_008um_00124_00223-1             203.95033             116.47465
#> s_008um_00131_00230-1             144.87809             104.29722
#> s_008um_00133_00224-1             194.63729             147.06553
#>                       s_008um_00115_00222-1 s_008um_00117_00224-1
#> s_008um_00110_00228-1              62.47689              64.49175
#> s_008um_00122_00239-1             147.07039             126.48453
#> s_008um_00125_00234-1             124.95606             102.44356
#> s_008um_00124_00223-1              72.43591              56.56270
#> s_008um_00131_00230-1             143.09626             121.84172
#> s_008um_00133_00224-1             144.87183             127.98700
#>                       s_008um_00133_00220-1 s_008um_00125_00243-1
#> s_008um_00110_00228-1             194.79286             169.69403
#> s_008um_00122_00239-1             175.62324              39.99751
#> s_008um_00125_00234-1             128.98684              71.99617
#> s_008um_00124_00223-1              75.88694             160.19157
#> s_008um_00131_00230-1              81.57965             114.53472
#> s_008um_00133_00224-1              31.99835             164.91325
#>                       s_008um_00109_00242-1 s_008um_00112_00231-1
#> s_008um_00110_00228-1              112.2792              28.84271
#> s_008um_00122_00239-1              106.7222             102.44241
#> s_008um_00125_00234-1              143.0940             106.72311
#> s_008um_00124_00223-1              193.6438             115.36666
#> s_008um_00131_00230-1              200.4596             152.19473
#> s_008um_00133_00224-1              239.9776             177.06942
#>                       s_008um_00122_00242-1 s_008um_00127_00219-1
#> s_008um_00110_00228-1             147.50318             153.86792
#> s_008um_00122_00239-1              23.99872             164.91442
#> s_008um_00125_00234-1              68.34757             121.05528
#> s_008um_00124_00223-1             152.83137              39.99687
#> s_008um_00131_00230-1             119.99047              93.63275
#> s_008um_00133_00224-1             168.74768              62.47749
#>                       s_008um_00121_00238-1 s_008um_00137_00248-1
#> s_008um_00110_00228-1             118.92016              268.7843
#> s_008um_00122_00239-1              11.31293              139.9315
#> s_008um_00125_00234-1              45.25091              147.5031
#> s_008um_00124_00223-1             122.36939              225.4115
#> s_008um_00131_00230-1             102.44059              151.7813
#> s_008um_00133_00224-1             147.50057              194.6384
#>                       s_008um_00136_00224-1 s_008um_00122_00236-1
#> s_008um_00110_00228-1             210.42540             115.36860
#> s_008um_00122_00239-1             164.13242              23.99873
#> s_008um_00125_00234-1             118.91806              28.84166
#> s_008um_00124_00223-1              96.32316             105.21765
#> s_008um_00131_00230-1              62.47694              86.52499
#> s_008um_00133_00224-1              23.99757             130.21963
#>                       s_008um_00120_00236-1 s_008um_00129_00243-1
#> s_008um_00110_00228-1             102.44243             193.64511
#> s_008um_00122_00239-1              28.84269              64.49275
#> s_008um_00125_00234-1              43.07694              78.78657
#> s_008um_00124_00223-1             108.80504             164.91578
#> s_008um_00131_00230-1             100.22985             105.21760
#> s_008um_00133_00224-1             141.52198             155.32284
#>                       s_008um_00118_00224-1 s_008um_00126_00248-1
#> s_008um_00110_00228-1              71.54705             204.88700
#> s_008um_00122_00239-1             124.18703              78.78654
#> s_008um_00125_00234-1              97.64659             112.27948
#> s_008um_00124_00223-1              48.65707             200.62860
#> s_008um_00131_00230-1             114.53271             149.44316
#> s_008um_00133_00224-1             119.98781             199.98768
#>                       s_008um_00127_00241-1 s_008um_00134_00222-1
#> s_008um_00110_00228-1             171.19463             197.88867
#> s_008um_00122_00239-1              43.07747             166.45634
#> s_008um_00125_00234-1              58.23786             119.99057
#> s_008um_00124_00223-1             145.97887              80.39075
#> s_008um_00131_00230-1              93.63157              68.34767
#> s_008um_00133_00224-1             144.21287              17.88732
#>                       s_008um_00110_00218-1 s_008um_00107_00226-1
#> s_008um_00110_00228-1              79.99585              28.84216
#> s_008um_00122_00239-1             193.48324             158.78407
#> s_008um_00125_00234-1             175.44209             157.56801
#> s_008um_00124_00223-1             118.91783             138.08711
#> s_008um_00131_00230-1             193.47841             194.62940
#> s_008um_00133_00224-1             190.13997             208.59301
#>                       s_008um_00117_00233-1 s_008um_00122_00221-1
#> s_008um_00110_00228-1              68.81333             111.12874
#> s_008um_00122_00239-1              62.47799             143.99245
#> s_008um_00125_00234-1              64.49167             106.72791
#> s_008um_00124_00223-1              97.64490              22.62589
#> s_008um_00131_00230-1             114.53071             101.81648
#> s_008um_00133_00224-1             146.84614              91.20551
#>                       s_008um_00116_00229-1 s_008um_00120_00224-1
#> s_008um_00110_00228-1              48.65734              86.15389
#> s_008um_00122_00239-1              93.28985             121.05579
#> s_008um_00125_00234-1              82.35824              89.43781
#> s_008um_00124_00223-1              79.99258              32.98145
#> s_008um_00131_00230-1             120.25429             100.23143
#> s_008um_00133_00224-1             141.74580             103.98944
#>                       s_008um_00136_00242-1 s_008um_00132_00236-1
#> s_008um_00110_00228-1              236.2175             187.25828
#> s_008um_00122_00239-1              114.5315              83.51384
#> s_008um_00125_00234-1              108.8034              58.23544
#> s_008um_00124_00223-1              179.7671             122.10764
#> s_008um_00131_00230-1              103.9944              48.65962
#> s_008um_00133_00224-1              145.9789              96.32755
#>                       s_008um_00127_00239-1 s_008um_00132_00227-1
#> s_008um_00110_00228-1             161.97483             176.16365
#> s_008um_00122_00239-1              39.99591             124.95378
#> s_008um_00125_00234-1              43.07902              79.18914
#> s_008um_00124_00223-1             130.22395              71.54814
#> s_008um_00131_00230-1              78.78554              25.29664
#> s_008um_00133_00224-1             129.23550              25.29665
#>                       s_008um_00116_00231-1 s_008um_00137_00230-1
#> s_008um_00110_00228-1              53.66108             216.57007
#> s_008um_00122_00239-1              79.99506             139.92929
#> s_008um_00125_00234-1              75.88771             101.18254
#> s_008um_00124_00223-1              90.50186             118.10879
#> s_008um_00131_00230-1             120.25399              47.99512
#> s_008um_00133_00224-1             147.06336              57.68542
#>                       s_008um_00119_00228-1 s_008um_00127_00231-1
#> s_008um_00110_00228-1              71.99265             138.08797
#> s_008um_00122_00239-1              91.20934              75.46619
#> s_008um_00125_00234-1              67.87763              28.84221
#> s_008um_00124_00223-1              56.56368              68.34846
#> s_008um_00131_00230-1              97.31471              32.98144
#> s_008um_00133_00224-1             116.46980              73.75031
#>                       s_008um_00132_00220-1 s_008um_00110_00223-1
#> s_008um_00110_00228-1             187.25614              39.99791
#> s_008um_00122_00239-1             171.75518             159.99016
#> s_008um_00125_00234-1             125.21115             148.79732
#> s_008um_00124_00223-1              68.34512             111.98860
#> s_008um_00131_00230-1              80.39466             177.07137
#> s_008um_00133_00224-1              32.98319             184.15527
#>                       s_008um_00108_00239-1 s_008um_00134_00245-1
#> s_008um_00110_00228-1              89.43754              235.2689
#> s_008um_00122_00239-1             111.98851              107.3221
#> s_008um_00125_00234-1             141.74568              113.6941
#> s_008um_00124_00223-1             181.00364              193.3182
#> s_008um_00131_00230-1             197.56527              122.3702
#> s_008um_00133_00224-1             233.21542              168.1816
#>                       s_008um_00121_00218-1 s_008um_00136_00234-1
#> s_008um_00110_00228-1             118.91803             213.44625
#> s_008um_00122_00239-1             168.18170             118.91639
#> s_008um_00125_00234-1             131.93270              87.99104
#> s_008um_00124_00223-1              46.64497             130.22144
#> s_008um_00131_00230-1             124.95609              51.22122
#> s_008um_00133_00224-1             107.32223              83.51817
#>                       s_008um_00132_00235-1 s_008um_00128_00235-1
#> s_008um_00110_00228-1             184.67732             154.49186
#> s_008um_00122_00239-1              86.15388              57.68331
#> s_008um_00125_00234-1              56.56297              25.29590
#> s_008um_00124_00223-1             115.37082             101.18765
#> s_008um_00131_00230-1              40.79008              46.64418
#> s_008um_00133_00224-1              88.35810              96.65785
#>                       s_008um_00135_00227-1 s_008um_00117_00242-1
#> s_008um_00110_00228-1             200.13943             125.21288
#> s_008um_00122_00239-1             141.52196              46.64305
#> s_008um_00125_00234-1              97.64327              90.50179
#> s_008um_00124_00223-1              93.62918             161.97719
#> s_008um_00131_00230-1              39.99631             147.49938
#> s_008um_00133_00224-1              28.84271             192.64942
#>                       s_008um_00133_00243-1 s_008um_00123_00220-1
#> s_008um_00110_00228-1             219.65512             122.10293
#> s_008um_00122_00239-1              93.62911             152.20225
#> s_008um_00125_00234-1              96.32643             113.13137
#> s_008um_00124_00223-1             175.44420              25.29693
#> s_008um_00131_00230-1             105.21817             102.44359
#> s_008um_00133_00224-1             151.99201              86.15503
#>                       s_008um_00136_00237-1 s_008um_00129_00239-1
#> s_008um_00110_00228-1             220.08902             175.62163
#> s_008um_00122_00239-1             113.12536              55.99427
#> s_008um_00125_00234-1              91.20546              51.22176
#> s_008um_00124_00223-1             147.50322             134.09751
#> s_008um_00131_00230-1              68.81442              73.75202
#> s_008um_00133_00224-1             106.72789             124.18593
#>                       s_008um_00114_00235-1 s_008um_00125_00241-1
#> s_008um_00110_00228-1              64.49440             158.78405
#> s_008um_00122_00239-1              71.54809              28.84214
#> s_008um_00125_00234-1              88.35374              55.99703
#> s_008um_00124_00223-1             124.95377             144.21460
#> s_008um_00131_00230-1             141.74575             100.23252
#> s_008um_00133_00224-1             175.61888             150.29607
#>                       s_008um_00113_00228-1 s_008um_00112_00222-1
#> s_008um_00110_00228-1              23.99755              50.59327
#> s_008um_00122_00239-1             113.69414             157.77565
#> s_008um_00125_00234-1             107.32217             141.52456
#> s_008um_00124_00223-1              96.65467              96.32314
#> s_008um_00131_00230-1             144.87178             164.90976
#> s_008um_00133_00224-1             163.15176             168.74340
#>                       s_008um_00126_00219-1 s_008um_00134_00219-1
#> s_008um_00110_00228-1             146.84614             205.03528
#> s_008um_00122_00239-1             163.15921             186.57678
#> s_008um_00125_00234-1             120.25994             139.93263
#> s_008um_00124_00223-1              35.77463              86.15397
#> s_008um_00131_00230-1              96.65919              91.20859
#> s_008um_00133_00224-1              68.81337              40.78984
#>                       s_008um_00129_00224-1 s_008um_00129_00247-1
#> s_008um_00110_00228-1             155.31583             214.94575
#> s_008um_00122_00239-1             132.41452              85.03558
#> s_008um_00125_00234-1              86.15701             108.80606
#> s_008um_00124_00223-1              40.78824             196.11237
#> s_008um_00131_00230-1              50.59383             136.93029
#> s_008um_00133_00224-1              31.99676             186.75118
#>                       s_008um_00130_00242-1 s_008um_00128_00248-1
#> s_008um_00110_00228-1             195.28979             215.24379
#> s_008um_00122_00239-1              68.34586              86.52803
#> s_008um_00125_00234-1              75.46742             114.53664
#> s_008um_00124_00223-1             159.39061             202.53344
#> s_008um_00131_00230-1              96.32749             145.97792
#> s_008um_00133_00224-1             145.97801             196.11094
#>                       s_008um_00135_00236-1 s_008um_00121_00247-1
#> s_008um_00110_00228-1             209.97114             175.62590
#> s_008um_00122_00239-1             106.72225              64.49441
#> s_008um_00125_00234-1              81.57643             108.80493
#> s_008um_00124_00223-1             136.22637             193.48337
#> s_008um_00131_00230-1              57.68539             157.77302
#> s_008um_00133_00224-1              97.31927             207.52324
#>                       s_008um_00130_00241-1 s_008um_00116_00234-1
#> s_008um_00110_00228-1             190.81468              67.87763
#> s_008um_00122_00239-1              65.96342              62.47744
#> s_008um_00125_00234-1              68.81441              71.99264
#> s_008um_00124_00223-1             151.78143             108.80325
#> s_008um_00131_00230-1              88.35804             124.18057
#> s_008um_00133_00224-1             138.09353             157.76935
#>                       s_008um_00109_00228-1 s_008um_00120_00245-1
#> s_008um_00110_00228-1              7.999182             157.77558
#> s_008um_00122_00239-1            136.225224              50.59320
#> s_008um_00125_00234-1            136.691769              96.65773
#> s_008um_00124_00223-1            126.478142             178.87513
#> s_008um_00131_00230-1            176.708123             148.79685
#> s_008um_00133_00224-1            194.628269             197.57069
#>                       s_008um_00127_00248-1 s_008um_00121_00235-1
#> s_008um_00110_00228-1             209.97690             104.29895
#> s_008um_00122_00239-1              82.36032              32.98314
#> s_008um_00125_00234-1             113.13123              32.98143
#> s_008um_00124_00223-1             201.42450              98.94864
#> s_008um_00131_00230-1             147.50396              89.43383
#> s_008um_00133_00224-1             197.89720             130.21908
#>                       s_008um_00136_00247-1 s_008um_00130_00236-1
#> s_008um_00110_00228-1              257.6002             172.30995
#> s_008um_00122_00239-1              128.9855              68.34505
#> s_008um_00125_00234-1              136.2263              43.07749
#> s_008um_00124_00223-1              214.6506             114.53638
#> s_008um_00131_00230-1              141.7530              48.65934
#> s_008um_00133_00224-1              185.5491              98.94866
#>                       s_008um_00137_00229-1 s_008um_00122_00233-1
#> s_008um_00110_00228-1             216.12625             103.99083
#> s_008um_00122_00239-1             144.20833              47.99746
#> s_008um_00125_00234-1             103.98951              25.29590
#> s_008um_00124_00223-1             114.53272              81.57961
#> s_008um_00131_00230-1              48.65708              75.88689
#> s_008um_00133_00224-1              51.22179             113.69105
#>                       s_008um_00137_00241-1 s_008um_00132_00228-1
#> s_008um_00110_00228-1              239.7127             175.98207
#> s_008um_00122_00239-1              121.0500             118.91856
#> s_008um_00125_00234-1              111.1305              73.74973
#> s_008um_00124_00223-1              177.6180              75.46585
#> s_008um_00131_00230-1              100.2341              17.88731
#> s_008um_00133_00224-1              139.7069              32.98290
#>                       s_008um_00126_00230-1 s_008um_00129_00220-1
#> s_008um_00110_00228-1             128.98336             164.90760
#> s_008um_00122_00239-1              78.78552             161.97727
#> s_008um_00125_00234-1              32.98287             116.47470
#> s_008um_00124_00223-1              58.23791              46.64313
#> s_008um_00131_00230-1              39.99593              81.58021
#> s_008um_00133_00224-1              73.74976              45.25178
#>                       s_008um_00108_00224-1 s_008um_00115_00223-1
#> s_008um_00110_00228-1              35.77513              56.56365
#> s_008um_00122_00239-1             164.13538             139.70649
#> s_008um_00125_00234-1             157.77186             118.92075
#> s_008um_00124_00223-1             128.23657              71.99268
#> s_008um_00131_00230-1             190.13991             139.70183
#> s_008um_00133_00224-1             199.97966             144.20757
#>                       s_008um_00130_00231-1 s_008um_00127_00236-1
#> s_008um_00110_00228-1             161.77410             150.29343
#> s_008um_00122_00239-1              90.50183              46.64308
#> s_008um_00125_00234-1              46.64310              22.62587
#> s_008um_00124_00223-1              79.99510             106.72789
#> s_008um_00131_00230-1              11.31274              57.68443
#> s_008um_00133_00224-1              60.92215             107.32382
#>                       s_008um_00132_00241-1 s_008um_00115_00224-1
#> s_008um_00110_00228-1             204.41429              51.22029
#> s_008um_00122_00239-1              81.57641             132.41637
#> s_008um_00125_00234-1              79.19054             113.12940
#> s_008um_00124_00223-1             157.57323              72.43561
#> s_008um_00131_00230-1              88.35833             136.69181
#> s_008um_00133_00224-1             136.22778             143.98537
#>                       s_008um_00112_00225-1 s_008um_00116_00224-1
#> s_008um_00110_00228-1              28.84221              57.68332
#> s_008um_00122_00239-1             137.62887             129.23710
#> s_008um_00125_00234-1             126.48133             107.62196
#> s_008um_00124_00223-1              97.31413              64.49141
#> s_008um_00131_00230-1             157.16027             129.23250
#> s_008um_00133_00224-1             168.17314             135.98618
#>                       s_008um_00121_00245-1 s_008um_00121_00225-1
#> s_008um_00110_00228-1             161.97808              91.20461
#> s_008um_00122_00239-1              48.65928             112.27956
#> s_008um_00125_00234-1              93.63152              78.78663
#> s_008um_00124_00223-1             177.61885              28.84168
#> s_008um_00131_00230-1             144.21100              89.43516
#> s_008um_00133_00224-1             193.48011              96.32286
#>                       s_008um_00133_00238-1 s_008um_00121_00242-1
#> s_008um_00110_00228-1             200.62142             142.42702
#> s_008um_00122_00239-1              88.35375              25.29661
#> s_008um_00125_00234-1              71.54810              71.54914
#> s_008um_00124_00223-1             139.93481             153.87435
#> s_008um_00131_00230-1              65.96631             124.95374
#> s_008um_00133_00224-1             111.99414             173.05328
#>                       s_008um_00120_00228-1 s_008um_00120_00239-1
#> s_008um_00110_00228-1              79.99183             118.92071
#> s_008um_00122_00239-1              89.43815              15.99836
#> s_008um_00125_00234-1              62.47802              56.56363
#> s_008um_00124_00223-1              51.22088             131.93150
#> s_008um_00131_00230-1              89.43404             113.69099
#> s_008um_00133_00224-1             108.80062             158.78234
#>                       s_008um_00132_00237-1 s_008um_00120_00232-1
#> s_008um_00110_00228-1             190.14099              86.15498
#> s_008um_00122_00239-1              81.57584              58.23786
#> s_008um_00125_00234-1              60.92084              43.07749
#> s_008um_00124_00223-1             128.98881              78.78557
#> s_008um_00131_00230-1              56.56565              89.43346
#> s_008um_00133_00224-1             104.30161             122.10295
#>                       s_008um_00119_00243-1 s_008um_00131_00243-1
#> s_008um_00110_00228-1             139.93476             206.43995
#> s_008um_00122_00239-1              39.99680              78.78397
#> s_008um_00125_00234-1              86.52658              86.52806
#> s_008um_00124_00223-1             164.91434             169.50809
#> s_008um_00131_00230-1             141.52245             103.99450
#> s_008um_00133_00224-1             188.79191             152.83138
#>                       s_008um_00125_00242-1 s_008um_00125_00224-1
#> s_008um_00110_00228-1              164.1348             124.18058
#> s_008um_00122_00239-1               33.9388             122.36938
#> s_008um_00125_00234-1               63.9966              79.99582
#> s_008um_00124_00223-1              152.2025              11.31294
#> s_008um_00131_00230-1              107.3238              67.87765
#> s_008um_00133_00224-1              157.5711              63.99351
#>                       s_008um_00121_00233-1 s_008um_00106_00238-1
#> s_008um_00110_00228-1              96.65599              86.15692
#> s_008um_00122_00239-1              48.65960             128.23677
#> s_008um_00125_00234-1              32.98172             155.31573
#> s_008um_00124_00223-1              83.51733             187.42892
#> s_008um_00131_00230-1              83.51386             209.96883
#> s_008um_00133_00224-1             119.98889             243.28638
#>                       s_008um_00119_00234-1 s_008um_00136_00241-1
#> s_008um_00110_00228-1              86.52645             232.53133
#> s_008um_00122_00239-1              46.64491             113.12592
#> s_008um_00125_00234-1              47.99510             104.29893
#> s_008um_00124_00223-1              96.65782             173.05619
#> s_008um_00131_00230-1             101.18251              96.65911
#> s_008um_00133_00224-1             137.62432             138.09439
#>                       s_008um_00116_00218-1 s_008um_00117_00227-1
#> s_008um_00110_00228-1              93.28838              56.56268
#> s_008um_00122_00239-1             174.71370             103.99444
#> s_008um_00125_00234-1             146.85223              85.03510
#> s_008um_00124_00223-1              75.46587              64.49178
#> s_008um_00131_00230-1             153.66372             114.53158
#> s_008um_00133_00224-1             144.20904             130.21712
#>                       s_008um_00136_00236-1 s_008um_00124_00220-1
#> s_008um_00110_00228-1             217.60338             128.98354
#> s_008um_00122_00239-1             114.53070             152.83141
#> s_008um_00125_00234-1              89.43403             112.27962
#> s_008um_00124_00223-1             141.52511              23.99876
#> s_008um_00131_00230-1              62.47801              97.64661
#> s_008um_00133_00224-1              98.94950              78.78405
#>                       s_008um_00124_00219-1 s_008um_00118_00241-1
#> s_008um_00110_00228-1             133.13380             122.10760
#> s_008um_00122_00239-1             160.78923              35.77351
#> s_008um_00125_00234-1             120.26023              79.18907
#> s_008um_00124_00223-1              31.99835             151.77975
#> s_008um_00131_00230-1             104.30119             136.22274
#> s_008um_00133_00224-1              82.35829             181.35744
#>                       s_008um_00132_00218-1 s_008um_00132_00240-1
#> s_008um_00110_00228-1             193.30940             200.46277
#> s_008um_00122_00239-1             186.06253              80.39097
#> s_008um_00125_00234-1             139.70470              73.75102
#> s_008um_00124_00223-1              75.46465             150.29817
#> s_008um_00131_00230-1              96.32760              80.39487
#> s_008um_00133_00224-1              48.65967             128.24286
#>                       s_008um_00125_00218-1 s_008um_00107_00222-1
#> s_008um_00110_00228-1             144.20836               53.6627
#> s_008um_00122_00239-1             169.69616              181.3608
#> s_008um_00125_00234-1             127.99335              173.0529
#> s_008um_00124_00223-1              40.78984              136.2214
#> s_008um_00131_00230-1             107.32541              202.3673
#> s_008um_00133_00224-1              79.99402              208.5936
#>                       s_008um_00126_00224-1 s_008um_00137_00240-1
#> s_008um_00110_00228-1             131.92575             236.35199
#> s_008um_00122_00239-1             124.18590             120.25426
#> s_008um_00125_00234-1              80.39462             107.32214
#> s_008um_00124_00223-1              17.88704             171.19687
#> s_008um_00131_00230-1              62.47803              93.28984
#> s_008um_00133_00224-1              55.99432             131.93264
#>                       s_008um_00133_00223-1 s_008um_00125_00222-1
#> s_008um_00110_00228-1            188.278183             129.23085
#> s_008um_00122_00239-1            155.319982             138.09353
#> s_008um_00125_00234-1            108.803292              95.99499
#> s_008um_00124_00223-1             71.992698              11.31274
#> s_008um_00131_00230-1             58.237363              79.99511
#> s_008um_00133_00224-1              7.999587              65.96347
#>                       s_008um_00123_00240-1 s_008um_00134_00225-1
#> s_008um_00110_00228-1             141.52451             193.47420
#> s_008um_00122_00239-1              11.31293             147.50056
#> s_008um_00125_00234-1              50.59323             101.81462
#> s_008um_00124_00223-1             136.22777              81.57647
#> s_008um_00131_00230-1             102.44170              46.64421
#> s_008um_00133_00224-1             150.93245              11.31294
#>                       s_008um_00108_00242-1 s_008um_00116_00221-1
#> s_008um_00110_00228-1              113.1307              73.75028
#> s_008um_00122_00239-1              114.5306             151.78146
#> s_008um_00125_00234-1              150.2912             126.48356
#> s_008um_00124_00223-1              198.6995              65.96346
#> s_008um_00131_00230-1              207.5173             139.93158
#> s_008um_00133_00224-1              246.4236             138.08803
#>                       s_008um_00123_00237-1 s_008um_00130_00229-1
#> s_008um_00110_00228-1             126.48131             160.18371
#> s_008um_00122_00239-1              17.88728             102.44170
#> s_008um_00125_00234-1              28.84220              56.56366
#> s_008um_00124_00223-1             112.27929              67.87765
#> s_008um_00131_00230-1              85.03355              11.31294
#> s_008um_00133_00224-1             131.19933              46.64421
#>                       s_008um_00129_00221-1 s_008um_00112_00221-1
#> s_008um_00110_00228-1             161.97117              58.23734
#> s_008um_00122_00239-1             154.49562             164.72081
#> s_008um_00125_00234-1             108.80508             147.06824
#> s_008um_00124_00223-1              43.07698              97.31473
#> s_008um_00131_00230-1              73.75264             168.17598
#> s_008um_00133_00224-1              39.99701             169.68899
#>                       s_008um_00129_00223-1 s_008um_00135_00238-1
#> s_008um_00110_00228-1             157.15885             215.38744
#> s_008um_00122_00239-1             139.70462             104.29647
#> s_008um_00125_00234-1              93.63163              86.15497
#> s_008um_00124_00223-1              39.99594             148.79952
#> s_008um_00131_00230-1              58.23791              71.55022
#> s_008um_00133_00224-1              32.98174             113.13134
#>                       s_008um_00132_00226-1 s_008um_00123_00228-1
#> s_008um_00110_00228-1             176.70756             103.98939
#> s_008um_00122_00239-1             131.19930              88.35805
#> s_008um_00125_00234-1              85.03413              50.59382
#> s_008um_00124_00223-1              68.34592              40.78982
#> s_008um_00131_00230-1              32.98289              65.96345
#> s_008um_00133_00224-1              17.88731              86.15394

Part VI: Save the SpatialNiche files

saveRDS(bcsHD, 'bcsHD.rds')
saveRDS(PeripheryBCs, 'PeripheryBCs.rds')
saveRDS(PeripheryGCs, 'PeripheryGCs.rds')
sessionInfo()
#> R version 4.4.0 (2024-04-24 ucrt)
#> Platform: x86_64-w64-mingw32/x64
#> Running under: Windows 11 x64 (build 22631)
#> 
#> Matrix products: default
#> 
#> 
#> locale:
#> [1] LC_COLLATE=English_United States.utf8 
#> [2] LC_CTYPE=English_United States.utf8   
#> [3] LC_MONETARY=English_United States.utf8
#> [4] LC_NUMERIC=C                          
#> [5] LC_TIME=English_United States.utf8    
#> 
#> time zone: America/New_York
#> tzcode source: internal
#> 
#> attached base packages:
#> [1] stats     graphics  grDevices utils     datasets  methods   base     
#> 
#> other attached packages:
#> [1] Seurat_5.2.1       SeuratObject_5.0.2 sp_2.2-0           scattermore_1.2   
#> [5] dplyr_1.1.4        ggplot2_3.5.2      SpatialNiche_0.1.0
#> 
#> loaded via a namespace (and not attached):
#>   [1] deldir_2.0-4           pbapply_1.7-2          gridExtra_2.3         
#>   [4] rlang_1.1.5            magrittr_2.0.3         RcppAnnoy_0.0.22      
#>   [7] spatstat.geom_3.3-6    matrixStats_1.5.0      ggridges_0.5.6        
#>  [10] compiler_4.4.0         reshape2_1.4.4         png_0.1-8             
#>  [13] vctrs_0.6.5            stringr_1.5.1          pkgconfig_2.0.3       
#>  [16] fastmap_1.2.0          labeling_0.4.3         utf8_1.2.6            
#>  [19] promises_1.3.2         rmarkdown_2.29         tzdb_0.5.0            
#>  [22] purrr_1.0.4            bit_4.6.0              xfun_0.52             
#>  [25] cachem_1.1.0           jsonlite_2.0.0         goftest_1.2-3         
#>  [28] later_1.4.1            spatstat.utils_3.1-3   jpeg_0.1-11           
#>  [31] tiff_0.1-12            irlba_2.3.5.1          parallel_4.4.0        
#>  [34] cluster_2.1.8.1        R6_2.6.1               ica_1.0-3             
#>  [37] spatstat.data_3.1-6    stringi_1.8.7          bslib_0.9.0           
#>  [40] RColorBrewer_1.1-3     reticulate_1.42.0      spatstat.univar_3.1-2 
#>  [43] parallelly_1.43.0      lmtest_0.9-40          jquerylib_0.1.4       
#>  [46] Rcpp_1.0.14            assertthat_0.2.1       knitr_1.50            
#>  [49] tensor_1.5             future.apply_1.11.3    zoo_1.8-13            
#>  [52] sctransform_0.4.1      httpuv_1.6.15          Matrix_1.7-3          
#>  [55] splines_4.4.0          igraph_2.1.4           tidyselect_1.2.1      
#>  [58] abind_1.4-8            rstudioapi_0.17.1      dichromat_2.0-0.1     
#>  [61] yaml_2.3.10            spatstat.random_3.3-3  spatstat.explore_3.4-2
#>  [64] codetools_0.2-20       miniUI_0.1.2           listenv_0.9.1         
#>  [67] plyr_1.8.9             lattice_0.22-7         tibble_3.2.1          
#>  [70] shiny_1.10.0           withr_3.0.2            ROCR_1.0-11           
#>  [73] evaluate_1.0.3         Rtsne_0.17             future_1.40.0         
#>  [76] fastDummies_1.7.5      survival_3.8-3         polyclip_1.10-7       
#>  [79] fitdistrplus_1.2-2     pillar_1.10.2          KernSmooth_2.23-26    
#>  [82] plotly_4.10.4          generics_0.1.4         RcppHNSW_0.6.0        
#>  [85] scales_1.4.0           globals_0.17.0         xtable_1.8-4          
#>  [88] glue_1.8.0             lazyeval_0.2.2         tools_4.4.0           
#>  [91] data.table_1.17.0      RSpectra_0.16-2        RANN_2.6.2            
#>  [94] bmp_0.3                dotCall64_1.2          cowplot_1.1.3         
#>  [97] grid_4.4.0             tidyr_1.3.1            colorspace_2.1-1      
#> [100] readbitmap_0.1.5       nlme_3.1-168           patchwork_1.3.0       
#> [103] cli_3.6.4              spatstat.sparse_3.1-0  spam_2.11-1           
#> [106] viridisLite_0.4.2      arrow_19.0.1           uwot_0.2.3            
#> [109] gtable_0.3.6           sass_0.4.10            digest_0.6.37         
#> [112] progressr_0.15.1       ggrepel_0.9.6          rjson_0.2.23          
#> [115] htmlwidgets_1.6.4      farver_2.1.2           htmltools_0.5.8.1     
#> [118] lifecycle_1.0.4        httr_1.4.7             mime_0.13             
#> [121] bit64_4.6.0-1          MASS_7.3-65